Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GPR3 | P46089 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.34 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4408 | 0.84 | KDM4E (0.57) | KDM4EGPR3TOP2ACYP1A2ALDH1A1 | |
| SCHEMBL26597 | 0.77 | KDM4E (0.57) | KDM4EGPR3TOP2API4KAPI4K2B | |
| SCHEMBL2514608 | 0.75 | KDM4E (0.50) | KDM4EGPR3TOP2ACYP1A2ALDH1A1 | |
| SCHEMBL28437178 | 0.74 | GPR3 (0.69) | KDM4EGPR3TOP2API4KAPI4K2B | |
| SCHEMBL22972 | 0.74 | ALDH1A1 (0.43) | KDM4EPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL27857583 | 0.74 | KDM4E (0.39) | KDM4EGPR3CYP1A2ALDH1A1MAPT | |
| SCHEMBL27158258 | 0.73 | ALDH1A1 (0.41) | KDM4EPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL17511855 | 0.71 | KDM4E (0.42) | KDM4EGPR3CYP1A2ALDH1A1MAPT | |
| SCHEMBL28260376 | 0.71 | KDM4E (0.45) | KDM4EGPR3TOP2ACYP1A2ALDH1A1 | |
| SCHEMBL12474840 | 0.69 | KDM4E (0.46) | KDM4EGPR3CYP1A2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155698-A1 | ORGANOBORON COMPOUNDS EXHIBITING ANTICOCCIDIAL ACTIVITIES | Nitto Kasei Co., Ltd. (JP) | 2001-11-21 | — | — | EP | disclosed |