SCHEMBL4408312

SCHEMBL4408312

CCCCCCCC(=O)NC1CC(C)(C)N(O)C(C)(C)C1

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 1/20 0.52
GNAO1 P09471 1/20 0.52
GNAI1 P63096 1/20 0.52
TRPV1 Q8NER1 6/20 0.50
CNR1 P21554 5/20 0.50
CNR2 P34972 5/20 0.50
EPHX2 P34913 1/20 0.48
NAAA Q02083 3/20 0.44
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MAPT P10636 1/20 0.43
HPGD P15428 1/20 0.43
KMT2A Q03164 1/20 0.43
HSP90AA1 P07900 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL271981 1.00 GNAI3 (0.52) GNAI3GNAO1GNAI1TRPV1CNR1
SCHEMBL23793654 1.00 GNAI3 (0.52) GNAI3GNAO1GNAI1TRPV1CNR1
SCHEMBL9403437 1.00 GNAI3 (0.52) GNAI3GNAO1GNAI1TRPV1CNR1
SCHEMBL8906309 1.00 GNAI3 (0.52) GNAI3GNAO1GNAI1TRPV1CNR1
SCHEMBL21236012 0.98 GNAI3 (0.50) GNAI3GNAO1GNAI1TRPV1CNR1
SCHEMBL23793834 0.94 GNAI3 (0.44) GNAI3GNAO1GNAI1TRPV1CNR1
SCHEMBL316348 0.92 SMN1; SMN2 (0.48) GNAI3GNAO1GNAI1TRPV1CNR1
SCHEMBL10495774 0.90 HMGCR (0.50) GNAI3GNAO1GNAI1TRPV1CNR1
SCHEMBL9403390 0.88 GNAI3 (0.52) GNAI3GNAO1GNAI1TRPV1CNR1
SCHEMBL10719860 0.88 GNAI3 (0.52) GNAI3GNAO1GNAI1TRPV1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2030963-A2 Derivatives of 1-oxyl-4-hydroxy-or 4-amino-2,2,6,6-tetramethylpiperidine as polymerization inhibitors for (meth) acrylate monomers Ciba Holding Inc. (CH) 2009-03-04 EP disclosed
EP-1095006-A1 DERIVATIVES OF 1-OXYL-4-HYDROXY-OR 4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINE AS POLYMERIZATION INHIBITORS FOR (METH) ACRYLATE MONOMERS Ciba SC Holding AG (CH) 2001-05-02 EP disclosed
EP-1000032-A1 INHIBITION OF PULP AND PAPER YELLOWING USING NITROXIDES AND OTHER COADDITIVES Ciba SC Holding AG (CH) 2000-05-17 EP disclosed
WO-2000003965-A1 DERIVATIVES OF 1-OXYL-4-HYDROXY- OR 4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINE AS POLYMERIZATION INHIBITORS FOR (METH)ACRYLATE MONOMERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-01-27 WO disclosed
US-5928558-A STORAGE STABILITY CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-07-27 US disclosed
WO-1999005108-A1 INHIBITION OF PULP AND PAPER YELLOWING USING NITROXIDES AND OTHER COADDITIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-02-04 WO disclosed