Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MC4R | P32245 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | UBE2M | P61081 | 1/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8210228 | 0.83 | MEN1 (0.43) | KMT2AMEN1MC4RLMNAMAPT | |
| Hydrochloric Acid SCHEMBL4386259 | 0.82 | MEN1 (0.42) | KMT2AMEN1MC4RLMNAMAPT | |
| SCHEMBL4385355 | 0.82 | CACNA1B (0.46) | KMT2AMEN1FFAR4S1PR1S1PR5 | |
| SCHEMBL4388294 | 0.80 | MEN1 (0.51) | KMT2AMEN1LMNAMAPTPOLB | |
| SCHEMBL4395353 | 0.80 | MEN1 (0.45) | KMT2AMEN1MC4RLMNAMAPT | |
| SCHEMBL8212151 | 0.80 | KMT2A (0.45) | KMT2AMEN1MC4RLMNAMAPT | |
| Hydrochloric Acid SCHEMBL4383617 | 0.79 | KMT2A (0.44) | KMT2AMEN1MC4RLMNAMAPT | |
| SCHEMBL4410979 | 0.79 | MEN1 (0.48) | KMT2AMEN1LMNAMAPTPOLB | |
| SCHEMBL4382633 | 0.78 | MEN1 (0.43) | KMT2AMEN1LMNAMAPTPOLB | |
| SCHEMBL13589563 | 0.77 | MC4R (0.47) | KMT2AMEN1MC4RLMNAUBE2M |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2040698-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008008398-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2008-01-17 | — | — | WO | disclosed |