Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4380358 | 0.89 | LMNA (0.51) | MEN1KMT2ANR4A2MGLLMRGPRX4 | |
| SCHEMBL4388294 | 0.88 | MEN1 (0.51) | MEN1KMT2ANR4A2IDO1PRKCA | |
| SCHEMBL4393140 | 0.87 | NR4A2 (0.46) | MEN1KMT2ANR4A2PRKCAPRKCD | |
| SCHEMBL4395452 | 0.86 | FAAH (0.63) | MEN1KMT2AFAAHSMN1; SMN2LMNA | |
| SCHEMBL4382642 | 0.86 | TACR1 (0.48) | MEN1KMT2ANR4A2IDO1PRKCA | |
| SCHEMBL4379562 | 0.85 | MEN1 (0.48) | MEN1KMT2ANR4A2IDO1PRKCA | |
| SCHEMBL4395320 | 0.85 | RAB9A (0.53) | MEN1KMT2APDGFRAS1PR1S1PR5 | |
| SCHEMBL13588940 | 0.85 | DPP4 (0.46) | MEN1KMT2AFFAR1FFAR4FAAH | |
| SCHEMBL4382696 | 0.84 | KMT2A (0.53) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL4387904 | 0.84 | MEN1 (0.47) | MEN1KMT2ANR4A2IDO1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2040698-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008008398-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2008-01-17 | — | — | WO | disclosed |