Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2200994 | 0.73 | ALDH1A1 (0.38) | LMNATSHRALDH1A1GAAKMT2A | |
| SCHEMBL9803234 | 0.72 | CYP2D6 (0.46) | LMNATSHRALDH1A1USP2ALOX15 | |
| SCHEMBL13556317 | 0.71 | ALDH1A1 (0.45) | LMNATSHRPOLBALDH1A1USP2 | |
| SCHEMBL10614240 | 0.71 | ALDH1A1 (0.42) | LMNATSHRPOLBALDH1A1USP2 | |
| SCHEMBL11323271 | 0.71 | ALDH1A1 (0.44) | LMNATSHRPOLBALDH1A1USP2 | |
| SCHEMBL6675357 | 0.70 | NPC1 (0.55) | LMNAALDH1A1USP2ALOX15TDP1 | |
| SCHEMBL20139152 | 0.70 | ALDH1A1 (0.42) | LMNATSHRPOLBALDH1A1USP2 | |
| SCHEMBL2597869 | 0.69 | ALDH1A1 (0.43) | ALDH1A1USP2ALOX15TDP1CYP2D6 | |
| SCHEMBL6036885 | 0.69 | NPC1 (0.56) | LMNATSHRPOLBALDH1A1USP2 | |
| SCHEMBL14818865 | 0.69 | ALDH1A1 (0.40) | LMNATSHRALDH1A1USP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009077608-A1 | 2 -AMINOPYRIMIDINE DERIVATIVES AS HISTAMINE H4 ANTAGONISTS | PALAU PHARMA, S. A. (ES) | 2009-06-25 | — | — | WO | disclosed |