SCHEMBL4409150

SCHEMBL4409150

Nc1ccc(N)c(C(=O)c2ccccc2N)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.59
RECQL P46063 3/20 0.59
POLB P06746 3/20 0.59
KMT2A Q03164 3/20 0.59
MEN1 O00255 2/20 0.59
THRB P10828 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
USP2 O75604 1/20 0.59
PKM P14618 1/20 0.59
APEX1 P27695 1/20 0.59
BLM P54132 1/20 0.59
MCL1 Q07820 1/20 0.59
GAA P10253 1/20 0.59
HSD17B10 Q99714 4/20 0.47
ALOX15 P16050 2/20 0.47
TP53 P04637 1/20 0.47
ALDH1A1 P00352 5/20 0.47
CFTR P13569 1/20 0.47
KDM4E B2RXH2 4/20 0.44
TNF P01375 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30790667 0.87 MAPT (0.74) MAPTRECQLPOLBTDP1GAA
SCHEMBL112507 0.87 MAPT (0.74) MAPTRECQLPOLBTDP1GAA
SCHEMBL1261171 0.85 RECQL (0.75) MAPTRECQLPOLBKMT2AMEN1
SCHEMBL29849818 0.85 RECQL (0.75) MAPTRECQLPOLBKMT2AMEN1
Ammonia Solution, Strong SCHEMBL10992665 0.84 MAPT (0.71) MAPTRECQLPOLBTDP1GAA
Hydrochloric Acid SCHEMBL11745887 0.84 MAPT (0.71) MAPTRECQLPOLBTDP1GAA
SCHEMBL8764887 0.84 MAPT (0.71) MAPTRECQLPOLBTDP1GAA
SCHEMBL5312884 0.82 MAPT (0.68) MAPTRECQLPOLBKMT2AMEN1
SCHEMBL17744776 0.80 MAPT (0.71) MAPTPOLBGAAHSD17B10ALOX15
SCHEMBL17744777 0.80 MAPT (0.65) MAPTRECQLPOLBTDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240052104-A1 DICARBONYL HALIDES, POLYMER COMPOSITIONS AND FILMS MADE THEREFROM U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-02-15 US disclosed
US-10946617-B2 Graphite laminated body DU PONT-TORAY CO., LTD. (JP) 2021-03-16 US disclosed
US-20160279902-A1 GRAPHITE LAMINATED BODY DU PONT-TORAY CO., LTD. (JP) 2016-09-29 US disclosed
US-20090118408-A1 Dielectric compositions containing coated filler and methods relating thereto E. I. DU PONT DE NEMOURS AND COMPANY 2009-05-07 US disclosed
EP-0902048-B1 High dielectric constant flexible polyimide film and process of preparation DU PONT (US) 2005-11-23 EP disclosed
EP-1103366-A1 OPEN TYPE POLYIMIDE MOLDED PRODUCT AND PRODUCTION METHOD THEREOF DU PONT-TORAY COMPANY, LTD. (JP) 2001-05-30 EP disclosed
US-6159611-A High dielectric constant flexible polyimide film and process of preparation E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-12-12 US disclosed
US-6150456-A ADHESIVE FILM AND FERROELECTRIC CERAMIC FILLER E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-11-21 US disclosed
EP-0474054-B1 Flexible multi-layer polyimide film laminates and preparation thereof DU PONT (US) 1995-12-06 EP disclosed
EP-0659553-A1 Coextruded multi-layer aromatic polyimide film and preparation thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-06-28 EP disclosed
EP-0488066-A1 Chemically etchable adhesives E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-06-03 EP disclosed
EP-0488062-A1 Laminates utilizing chemically etchable adhesives E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-06-03 EP disclosed
EP-0483699-A1 Reactive-oligoimide adhesives, laminates, and methods of making the laminates E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-05-06 EP disclosed
US-5096998-A Unsaturated imide end groups, multilayer flexible metal-clad laminates E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-03-17 US disclosed
EP-0474054-A2 Flexible multi-layer polyimide film laminates and preparation thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-03-11 EP disclosed
US-5089628-A Heat resistance, moisture resistance, low dielectric constants CENTRAL GLASS COMPANY, LIMITED (JP) 1992-02-18 US disclosed
US-5084345-A Laminates utilizing chemically etchable adhesives E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-01-28 US disclosed
EP-0032745-B1 ETHER IMIDES AND PROCESS FOR PRODUCING THE SAME Hitachi, Ltd. (JP) 1987-01-07 EP disclosed
US-4460783-A AMIDATION, CYCLIZATION, DEHYDRATION HITACHI, LTD. (JP) 1984-07-17 US disclosed
EP-0032745-A2 Ether imides and process for producing the same Hitachi, Ltd. (JP) 1981-07-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240052104-A1 DICARBONYL HALIDES, POLYMER COMPOSITIONS AND FILMS MADE THEREFROM PUF60, PICALM, PARG MAPT 976/4885RECQL 4247/4885POLB 3751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.