Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4409208 | 0.81 | DPP7 (0.36) | DPP7PRCPNOS2NOS3NOS1 | |
| SCHEMBL28861849 | 0.79 | DPP7 (0.37) | DPP7PRCPALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL30866235 | 0.75 | DPP7 (0.47) | DPP7PRCPNOS2NOS3NOS1 | |
| SCHEMBL21955441 | 0.75 | DPP7 (0.47) | DPP7PRCPNOS2NOS3NOS1 | |
| SCHEMBL25728331 | 0.75 | DPP7 (0.47) | DPP7PRCPNOS2NOS3NOS1 | |
| SCHEMBL16853543 | 0.74 | DPP7 (0.49) | DPP7PRCPCTSCCYP1A2CYP3A4 | |
| SCHEMBL5493484 | 0.73 | NPSR1 (0.33) | NPSR1CTSC | |
| SCHEMBL5493485 | 0.73 | NPSR1 (0.33) | NPSR1CTSC | |
| SCHEMBL30729269 | 0.73 | DPP7 (0.48) | DPP7PRCPALDH1A1SMN1; SMN2CTSC | |
| SCHEMBL30729221 | 0.73 | DPP7 (0.48) | DPP7PRCPALDH1A1SMN1; SMN2CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7608577-B2 | Peptidyl ketones as inhibitors of DPIV | OSI PHARMACEUTICALS, INC. (US) | 2009-10-27 | — | — | US | disclosed |