SCHEMBL4409373

SCHEMBL4409373

CCC(=C(C)C(=O)O)N(CCOC)CCOC

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 1/20 0.35
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
ALDH1A1 P00352 2/20 0.31
KDM4E B2RXH2 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
HDAC1 Q13547 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4615318 0.81
SCHEMBL3227783 0.80 CA12 (0.41) MLYCDALDH1A1HPGDTSHR
SCHEMBL5065747 0.80 CA12 (0.41) MLYCDALDH1A1HPGDTSHR
SCHEMBL3278807 0.77 CA12 (0.45) ALDH1A1HPGDTSHR
SCHEMBL3219323 0.77 CA12 (0.45) ALDH1A1HPGDTSHR
SCHEMBL119068 0.76 LMNA (0.36) ALDH1A1HPGD
SCHEMBL1650860 0.76 LMNA (0.36) ALDH1A1HPGD
SCHEMBL3819591 0.76 FNTA (0.44) ALDH1A1TSHR
SCHEMBL6450984 0.74 FNTA (0.47) ALDH1A1TSHR
SCHEMBL7178901 0.74 FNTA (0.47) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1286823-B1 OPHTHALMIC LENSES AND COMPOSITIONS, AND METHODS FOR PRODUCING SAME COOPERVISION INT HOLDING CO LP (BB) 2009-06-17 EP disclosed
US-7262232-B2 Ophthalmic lenses and compositions and methods for producing same COOPERVISION, INC. (US) 2007-08-28 US disclosed
US-6992118-B2 Ophthalmic lenses and compositions and methods for producing same COOPER VISION INC. (US) 2006-01-31 US disclosed
US-20050191335-A1 Ophthalmic lenses and compositions and methods for producing same COOPERVISION INC. (US) 2005-09-01 US disclosed
US-20040046932-A1 Ophthalmic lenses and compositions and methods for producing same OCULAR SCIENCES, INC. 2004-03-11 US disclosed
US-6617373-B2 First crosslinked polymer material which is water swellable, and a second polymeric material physically imobilized by the first OCULAR SCIENCES, INC. 2003-09-09 US disclosed
US-20020091175-A1 Ophthalmic lenses and compositions and methods for producing same OCULAR SCIENCES, INC. 2002-07-11 US disclosed
US-6372815-B1 IMMOBILIZED WATER SWELLING POLYMER COOPERVISION INTERNATIONAL LIMITED (GB) 2002-04-16 US disclosed
EP-0751406-A2 Balanced charge polymer and hydrophilic contact lens manufactured therefrom Hydron Limited (GB) 1997-01-02 EP disclosed
EP-0563299-A4 BALANCED CHARGE POLYMER AND HYDROPHILIC CONTACT LENS MANUFACTURED THEREFROM CESKOSLOVENSKA AKADEMIE VED (CS) 1994-07-20 EP disclosed
US-5270415-A Balanced charge polymer and hydrophilic contact lens manufactured therefrom ALLERGAN INC. (US) 1993-12-14 US disclosed
EP-0563299-A1 BALANCED CHARGE POLYMER AND HYDROPHILIC CONTACT LENS MANUFACTURED THEREFROM Hydron Limited (GB) 1993-10-06 EP disclosed
WO-1992011301-A1 BALANCED CHARGE POLYMER AND HYDROPHILIC CONTACT LENS MANUFACTURED THEREFROM ALLERGAN, INC. (US) 1992-07-09 WO disclosed