Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11305042 | 0.81 | CYP2C19 (0.71) | TSHRCYP2D6CYP2C19HIF1AKDM4E | |
| SCHEMBL1370276 | 0.80 | — | — | |
| SCHEMBL4902244 | 0.73 | — | — | |
| SCHEMBL28180624 | 0.73 | — | — | |
| SCHEMBL12404473 | 0.71 | — | — | |
| SCHEMBL27770098 | 0.70 | TSHR (0.42) | TSHRCYP2D6CYP2C19HIF1AKDM4E | |
| SCHEMBL28113103 | 0.70 | TSHR (0.42) | TSHRCYP2D6CYP2C19HIF1AKDM4E | |
| SCHEMBL4905241 | 0.70 | TSHR (0.42) | TSHRCYP2D6CYP2C19HIF1AKDM4E | |
| SCHEMBL3697055 | 0.69 | HMGCR (0.41) | TSHRCYP2D6CYP2C19HIF1AKDM4E | |
| SCHEMBL126086 | 0.69 | TET2 (0.60) | TSHRCYP2D6CYP2C19HIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635572-B2 | Methods for conducting assays for enzyme activity on protein microarrays | Life Technologies Corporation (US) | 2009-12-22 | — | — | US | disclosed |
| US-20050118665-A1 | Methods for conducting assays for enzyme activity on protein microarrays | PROTOMETRIX, INC. | 2005-06-02 | — | — | US | disclosed |