SCHEMBL1370276

SCHEMBL1370276

CC(CN)(CN)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4902244 0.86
SCHEMBL28180624 0.86
SCHEMBL11305042 0.84 CYP2C19 (0.71)
SCHEMBL12404473 0.84
SCHEMBL4905241 0.82 TSHR (0.42)
SCHEMBL4409378 0.80 TSHR (0.46)
SCHEMBL4902448 0.78 FDPS (0.42)
SCHEMBL19133933 0.77 CYP2D6 (0.38)
SCHEMBL434731 0.75
SCHEMBL7335868 0.75 KDM4E (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12527880-B2 Cyanine-based telodendrimers and uses for treating cancer THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-01-20 US claimed
US-20250000811-A1 TELODENDRIMER NANOCARRIERS FOR MONOMERIC AMPHOTERICIN B DELIVERY UNIV NEW YORK STATE RES FOUND (US) 2025-01-02 US claimed
US-11649326-B2 Functional, segregated, charged telodendrimers and nanocarriers and methods of making and using same THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2023-05-16 US claimed
US-20230076792-A1 SEQUENTIAL TARGETING IN CROSSLINKING NANO-THERANOSTICS FOR TREATING BRAIN TUMORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-03-09 US claimed
CN-115551917-A Sequential targeting of cross-linked nanotherapeutics for the treatment of brain tumors 加利福尼亚大学董事会 2022-12-30 CN claimed
EP-4077477-A1 SEQUENTIAL TARGETING IN CROSSLINKING NANO-THERANOSTICS FOR TREATING BRAIN TUMORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-10-26 EP claimed
US-11406714-B2 Telodendrimers and nanocarriers and methods of using same THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2022-08-09 US claimed
EP-3347053-B1 FUNCTIONAL, SEGREGATED, CHARGED TELODENDRIMERS AND NANOCARRIERS AND METHODS OF MAKING AND USING SAME THE RESEARCH FOUNDATION FOR STATE UNIV OF NEW YORK (US) 2022-05-25 EP claimed
US-11219692-B2 Porphyrin modified telodendrimers THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-01-11 US claimed
US-20210346518-A1 CYANINE-BASED TELODENDRIMERS AND USES FOR TREATING CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2021-11-11 US claimed
WO-2015027054-A2 TELODENDRIMERS AND NANOCARRIERS AND METHODS OF USING SAME THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2015-02-26 WO claimed
US-20150056139-A1 TELODENDRIMERS AND NANOCARRIERS AND METHODS OF USING SAME NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-02-26 US claimed
US-20150045419-A1 REVERSIBLY CROSSLINKED MICELLE SYSTEMS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-02-12 US claimed
US-20140363371-A1 TELODENDRIMERS WITH ENHANCED DRUG DELIVERY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2014-12-11 US claimed
EP-2793953-A1 TELODENDRIMERS WITH ENHANCED DRUG DELIVERY The Regents of The University of California (US) 2014-10-29 EP claimed
US-20140161719-A1 PORPHYRIN MODIFIED TELODENDRIMERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-06-12 US claimed
WO-2013096388-A1 TELODENDRIMERS WITH ENHANCED DRUG DELIVERY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-06-27 WO claimed
US-20110286915-A1 Nanocarriers for Drug Delivery THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-11-24 US claimed
EP-2344134-A2 NANOCARRIERS FOR DRUG DELIVERY The Regents of the University of California (US) 2011-07-20 EP claimed
WO-2010039496-A2 NANOCARRIERS FOR DRUG DELIVERY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-04-08 WO claimed