SCHEMBL440940

SCHEMBL440940

NP(=O)(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL454419 0.88
SCHEMBL8827943 0.78
SCHEMBL3823153 0.78
SCHEMBL431641 0.78
SCHEMBL29034710 0.75
SCHEMBL98 0.72
SCHEMBL6704332 0.72 TP53 (0.31)
SCHEMBL50123 0.72
SCHEMBL17004026 0.72
SCHEMBL6068389 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122011028-A Method for efficiently preparing various substituted chiral phosphoramides 上海交通大学 2026-05-12 CN claimed
CN-117089061-A Flame-retardant polyester polyol and preparation method and application thereof 万华化学集团股份有限公司 2023-11-21 CN claimed
CN-109134380-A Chloro aminooimidazole class compound and preparation method thereof, purposes and detection method 上海慈瑞医药科技股份有限公司 2019-01-04 CN claimed
CN-108350005-A Chiral reagents for the preparation of homogeneous oligomers 卫材R&D管理有限公司 2018-07-31 CN claimed
CN-101117332-B Preparation method of 2-chloronicotinic acid ZHEJIANG MED XINCHANG PHARM 2012-03-28 CN claimed
CN-101117332-A Preparation method of 2-chloronicotinic acid ZHEJIANG MEDICINE CO LTD (CN) 2008-02-06 CN claimed
CN-1872800-A Long acting urea, method of preparation, and synthesizing N alkyl thiophosphoryl triamide of urease inhibitor DALIAN LIGHT IND COLLEGE (CN) 2006-12-06 CN claimed
EP-0320942-A2 Novel polysaccharides novel macromolecular conjugates of the polysaccharides AMERICAN CYANAMID COMPANY (US) 1989-06-21 EP claimed
JP-1238594-A None JP disclosed
CN-122011028-A Method for efficiently preparing various substituted chiral phosphoramides 上海交通大学 2026-05-12 CN disclosed
CN-122011028-A Method for efficiently preparing various substituted chiral phosphoramides 上海交通大学 2026-05-12 CN disclosed
US-12378267-B2 Synthesis of FMOC-protected morpholino monomers and oligomers ENTRADA THERAPEUTICS, INC. (US) 2025-08-05 US disclosed
US-20250241940-A1 MODIFIED ANTISENSE OLIGOMERS FOR EXON INCLUSION IN SPINAL MUSCULAR ATROPHY JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT 2025-07-31 US disclosed
US-12121532-B2 Modified antisense oligomers for exon inclusion in spinal muscular atrophy SAREPTA THERAPEUTICS, INC. (US) 2024-10-22 US disclosed
US-4233434-A POLYMERS AND COPOLYMERS FOR USE AS FILMS, MEMBRANES, FIBERS, AND SHAPED OBJECTS A.T. RAMOT PLASTICS LTD. (IL) 1980-11-11 US disclosed
US-4193805-A Flame retardant regenerated cellulose containing a phosphoric acid or thiophosphoric acid amide SANDOZ LTD. (CH) 1980-03-18 US disclosed
US-4098819-A PROCESS FOR THE PRODUCTION OF PHOSPHORIC ACID-DIMETHYLAMIDE-DICHLORIDE OR PHOSPHORIC ACID-BIS-(DIMETHYLAMIDE)-CHLORIDE WACKER-CHEMIE GMBH (DE) 1978-07-04 US disclosed
US-4079035-A Halophenoxyphosphazene fire retardants and polyesters containing same ETHYL CORPORATION (US) 1978-03-14 US disclosed
US-3937765-A REACTING A PHENOL AND A N,N-DIALKYL PHOSPHOAMIDIC HALIDE STAUFFER CHEMICAL COMPANY (US) 1976-02-10 US disclosed
US-3912769-A N-(4-sulfanilylphenyl) phosphoric acid triamides MERCK & CO INC 1975-10-14 US disclosed