SCHEMBL454419

SCHEMBL454419

NP(N)(=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL440940 0.88
SCHEMBL3823153 0.78
SCHEMBL431641 0.78
SCHEMBL8827943 0.78
SCHEMBL29034710 0.75
SCHEMBL6704332 0.72 TP53 (0.31)
SCHEMBL50123 0.72
SCHEMBL98 0.72
SCHEMBL17004026 0.72
SCHEMBL6068389 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105348505-A Preparation method for o-diaminobenzene phosphoryl chloride 3-butylene-1-amide polycarbonate ANHUI XINGXIN CHEMICAL TECHNOLOGY CO LTD 2016-02-24 CN claimed
CN-105294767-A Preparation method of o-phenylenediamine phosphoryl chloride 3-cyclohexene-1-methnol ester ANHUI XINGXIN CHEMICAL TECHNOLOGY CO LTD 2016-02-03 CN claimed
CN-101638421-B Preparation method of o-diaminobenzene phosphorylchloride condensed pentaerythritol ester ANHUI ZHONGDING SEALING PARTS 2012-10-03 CN claimed
CN-101638421-A Preparation method of o-diaminobenzene phosphorylchloride condensed pentaerythritol ester ANHUI ZHONGDING SEALING PARTS 2010-02-03 CN claimed
CN-1823074-A Process for synthesizing beta-lactamase inhibitor intermediates WYETH CORP (US) 2006-08-23 CN claimed
CN-1823069-A Process for synthesizing beta-lactamase inhibitor intermediates WYETH CORP (US) 2006-08-23 CN claimed
US-5114538-A Treating cellulose fibers with cationic papermaking stock adding a reactive sizing agent, forming a web and reacting the size EXXON CHEMICAL PATENTS INC. (US) 1992-05-19 US claimed
EP-4658280-A2 SIX MEMBERED RING CONTAINING OLIGOMERS Alnylam Pharmaceuticals, Inc. (US) 2025-12-10 EP disclosed
US-20250263696-A1 PROTEIN TRANSLATION SYSTEM TSINGHUA UNIVERSITY (CN) 2025-08-21 US disclosed
CN-119930689-B Synthetic method of bio-based phosphorus-nitrogen synergistic flame retardant and high-flame-retardance polymer composition prepared by using same 浙江嘉民新材料有限公司 2025-07-08 CN disclosed
CN-119930689-A Synthetic method of bio-based phosphorus-nitrogen synergistic flame retardant and high-flame-retardance polymer composition prepared by using same 浙江嘉民新材料有限公司 2025-05-06 CN disclosed
WO-2024163762-A2 SIX MEMBERED RING CONTAINING OLIGOMERS ALNYLAM PHARMACEUTICALS, INC. (US) 2024-08-08 WO disclosed
CN-111194217-B 4 '-fluoro-2' -methyl substituted nucleoside derivatives as inhibitors of HCV RNA replication 里伯赛恩斯有限责任公司 2024-01-12 CN disclosed
WO-1991010777-A1 PROCESS FOR SIZING PAPER AND SIMILAR PRODUCTS EXXON CHEMICAL PATENTS INC. (US) 1991-07-25 WO disclosed
US-4952717-A Myoinositol derivatives and preparation process thereof MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1990-08-28 US disclosed
EP-0348127-A2 Process for sizing paper and similar products EXXON CHEMICAL PATENTS INC. (US) 1989-12-27 EP disclosed
EP-0262227-A1 Process for the preparation of myoinositol derivatives MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-04-06 EP disclosed
US-4588812-A Substituted 2,3-dihydro-5H-thiazolo[2,3,-b]quinazoline derivatives PENNWALT CORPORATION (US) 1986-05-13 US disclosed
US-4193805-A Flame retardant regenerated cellulose containing a phosphoric acid or thiophosphoric acid amide SANDOZ LTD. (CH) 1980-03-18 US disclosed
US-4098819-A PROCESS FOR THE PRODUCTION OF PHOSPHORIC ACID-DIMETHYLAMIDE-DICHLORIDE OR PHOSPHORIC ACID-BIS-(DIMETHYLAMIDE)-CHLORIDE WACKER-CHEMIE GMBH (DE) 1978-07-04 US disclosed