⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11456391 | 0.97 | — | — | |
| SCHEMBL11468912 | 0.81 | TSHR (0.38) | — | |
| SCHEMBL11346817 | 0.81 | TSHR (0.38) | — | |
| SCHEMBL988919 | 0.80 | — | — | |
| SCHEMBL23725742 | 0.79 | — | — | |
| SCHEMBL27901748 | 0.79 | — | — | |
| SCHEMBL3504870 | 0.79 | — | — | |
| SCHEMBL28465342 | 0.79 | — | — | |
| SCHEMBL10331178 | 0.78 | TSHR (0.58) | — | |
| SCHEMBL10793944 | 0.78 | TSHR (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115724808-B | Olefin epoxidation method | 中国石油化工股份有限公司 | 2024-05-17 | — | — | CN | claimed |
| CN-108347916-A | Composition and method for reducing ice crystal formation | 先时迈纳米生物科技股份有限公司 | 2018-07-31 | — | — | CN | claimed |
| EP-2582799-B1 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF (S)-3-(1-AMINOETHYL)-PHENOL | CODEXIS INC (US) | 2017-12-20 | — | — | EP | claimed |
| US-8852900-B2 | Biocatalysts and methods for the synthesis of (S)-3-(1-aminoethyl)-phenol | CODEXIS, INC. (US) | 2014-10-07 | — | — | US | claimed |
| EP-2582799-A2 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF (S)-3-(1-AMINOETHYL)-PHENOL | Codexis, Inc. (US) | 2013-04-24 | — | — | EP | claimed |
| US-20130089898-A1 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF (S)-3-(1-AMINOETHYL)-PHENOL | CODEXIS, INC. (US) | 2013-04-11 | — | — | US | claimed |
| WO-2011159910-A2 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF (S)-3-(1-AMINOETHYL)-PHENOL | CODEXIS, INC. (US) | 2011-12-22 | — | — | WO | claimed |
| US-20110015395-A1 | PYRAZOLE COMPOUNDS WITH INHIBITORY ACTIVITY AGAINST ROS KINASE | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2011-01-20 | — | — | US | claimed |
| US-12378537-B2 | Biocatalysts and methods for synthesizing derivatives of tryptamine and tryptamine analogs | CODEXIS, INC. (US) | 2025-08-05 | — | — | US | disclosed |
| US-20250188502-A1 | BIOCATALYST AND METHOD FOR THE SYNTHESIS OF UBROGEPANT INTERMEDIATES | ENZYMASTER (NINGBO) BIO-ENGINEERING CO., LTD. (CN) | 2025-06-12 | — | — | US | disclosed |
| US-12305201-B2 | Engineered biocatalysts and methods for synthesizing chiral amines | CODEXIS, INC. (US) | 2025-05-20 | — | — | US | disclosed |
| EP-4490281-A1 | BIOCATALYST AND METHOD FOR THE SYNTHESIS OF UBROGEPANT INTERMEDIATES | Enzymaster (Ningbo) Bio-Engineering Co., Ltd. (CN) | 2025-01-15 | — | — | EP | disclosed |
| CN-115724808-B | Olefin epoxidation method | 中国石油化工股份有限公司 | 2024-05-17 | — | — | CN | disclosed |
| US-11932886-B2 | Engineered transaminase polypeptides and uses thereof | ENZYMASTER (NINGBO) BIO-ENGINEERING CO., LTD. (CN) | 2024-03-19 | — | — | US | disclosed |
| EP-0537318-A1 | NEW NON-HYGROSCOPIC MONO-AMMONIUM SALTS. | ALKALOIDA VEGYESZETI GYAR (HU) | 1993-04-21 | — | — | EP | disclosed |
| WO-1992018513-A1 | NEW NON-HYGROSCOPIC MONO-AMMONIUM SALTS | ALKALOIDA VEGYÉSZETI GYÁR RT. (HU) | 1992-10-29 | — | — | WO | disclosed |
| EP-0042626-B1 | ANTICONVULSIVE COMPOSITIONS | NEW YORK UNIVERSITY (US) | 1986-05-21 | — | — | EP | disclosed |
| US-4372974-A | Anticonvulsive compositions and method of treating convulsive disorders | NEW YORK UNIVERSITY (US) | 1983-02-08 | — | — | US | disclosed |
| US-4322440-A | Anticonvulsive compositions and method of treating convulsive disorders | NEW YORK UNIVERSITY (US) | 1982-03-30 | — | — | US | disclosed |
| EP-0042626-A2 | Anticonvulsive compositions | NEW YORK UNIVERSITY (US) | 1981-12-30 | — | — | EP | disclosed |