⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10796086 | 0.85 | TSHR (0.58) | — | |
| SCHEMBL10793944 | 0.85 | TSHR (0.58) | — | |
| SCHEMBL10804192 | 0.85 | TSHR (0.58) | — | |
| SCHEMBL28115216 | 0.81 | — | — | |
| SCHEMBL27507090 | 0.81 | — | — | |
| SCHEMBL28084284 | 0.80 | TSHR (0.54) | — | |
| SCHEMBL44095 | 0.80 | — | — | |
| SCHEMBL28084282 | 0.80 | TSHR (0.54) | — | |
| SCHEMBL11425834 | 0.78 | TSHR (0.52) | — | |
| SCHEMBL5610948 | 0.78 | TSHR (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110015395-A1 | PYRAZOLE COMPOUNDS WITH INHIBITORY ACTIVITY AGAINST ROS KINASE | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2011-01-20 | — | — | US | claimed |
| CN-120081706-A | Nutrient moisturizing ceramsite and preparation method, application and application method thereof | 鄂尔多斯应用技术学院 | 2025-06-03 | — | — | CN | disclosed |
| US-8273880-B2 | Pyrazole compounds with inhibitory activity against ROS kinase | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2012-09-25 | — | — | US | disclosed |
| US-20110015395-A1 | PYRAZOLE COMPOUNDS WITH INHIBITORY ACTIVITY AGAINST ROS KINASE | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2011-01-20 | — | — | US | disclosed |
| US-5726241-A | Finishing oil for precursor for high performance carbon fibers and precursor | HEXCEL CORPORATION (US) | 1998-03-10 | — | — | US | disclosed |