Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | GSK3A | P49840 | 6/20 | 0.46 |
| ▸ | GSK3B | P49841 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL79670 | 0.91 | KMT2A (0.53) | KMT2AMEN1GSK3AGSK3BMAPT | |
| SCHEMBL5489285 | 0.73 | GSK3A (0.52) | KMT2AMEN1GSK3AGSK3BMAPT | |
| SCHEMBL2319507 | 0.73 | KMT2A (0.47) | KMT2AMEN1GSK3AGSK3BMAPT | |
| SCHEMBL1043064 | 0.73 | MAPT (0.49) | KMT2AMEN1GSK3AGSK3BMAPT | |
| 3-Methyl-Rhodanine SCHEMBL25418661 | 0.72 | GSK3A (0.80) | KMT2AMEN1GSK3AGSK3BMAPT | |
| Isothiocyanate SCHEMBL6692342 | 0.70 | GSK3A (0.40) | KMT2AMEN1GSK3AGSK3BMAPT | |
| SCHEMBL5484818 | 0.69 | GSK3A (0.52) | KMT2AMEN1GSK3AGSK3BMAPT | |
| SCHEMBL5484387 | 0.69 | KMT2A (0.49) | KMT2AMEN1GSK3AGSK3BMAPT | |
| SCHEMBL5489520 | 0.69 | GSK3A (0.47) | KMT2AMEN1GSK3AGSK3BMAPT | |
| SCHEMBL5554090 | 0.69 | MAPT (0.44) | KMT2AMEN1GSK3AGSK3BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090017556-A1 | METHODS AND COMPLEXES INVOLVING IMMUNOGLOBULIN MOLECULE | NORTH CAROLINA A&T STATE UNIVERSITY | 2009-01-15 | — | — | US | disclosed |