Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 12/20 | 0.70 |
| ▸ | SCARB1 | Q8WTV0 | 8/20 | 0.59 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.55 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.55 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4410021 | 0.92 | MAPK14 (0.70) | MAPK14SCARB1MAPK13MAPK12MAPK11 | |
| SCHEMBL4958441 | 0.91 | MAPK14 (0.78) | MAPK14SCARB1MAPK13MAPK12MAPK11 | |
| SCHEMBL4410017 | 0.86 | MAPK14 (0.69) | MAPK14SCARB1MAPK13MAPK12MAPK11 | |
| SCHEMBL12669910 | 0.86 | MAPK14 (0.79) | MAPK14SCARB1MAPK13MAPK12MAPK11 | |
| SCHEMBL1599085 | 0.83 | MAPK14 (0.65) | MAPK14SCARB1 | |
| SCHEMBL1600560 | 0.83 | MAPK14 (1.00) | MAPK14SCARB1 | |
| SCHEMBL1602454 | 0.82 | MAPK14 (0.86) | MAPK14SCARB1MAPK13MAPK12MAPK11 | |
| Hydrochloric Acid SCHEMBL1899167 | 0.82 | MAPK14 (0.98) | MAPK14SCARB1 | |
| SCHEMBL1601028 | 0.82 | MAPK14 (0.86) | MAPK14SCARB1MAPK13MAPK12MAPK11 | |
| SCHEMBL1902717 | 0.80 | MAPK14 (0.72) | MAPK14SCARB1MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035005-A2 | THERAPY USING CYTOKINE INHIBITORS | Kemia, INC. (US) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007146712-A2 | THERAPY USING CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007058990-A2 | THERAPY USING CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-24 | — | — | WO | disclosed |