Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.78 |
| ▸ | SCARB1 | Q8WTV0 | 7/20 | 0.63 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.61 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.61 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1599085 | 0.92 | MAPK14 (0.65) | MAPK14SCARB1 | |
| SCHEMBL4410018 | 0.91 | MAPK14 (0.70) | MAPK14SCARB1MAPK13MAPK12MAPK11 | |
| SCHEMBL4410017 | 0.91 | MAPK14 (0.69) | MAPK14SCARB1MAPK13MAPK12MAPK11 | |
| SCHEMBL12669910 | 0.91 | MAPK14 (0.79) | MAPK14SCARB1MAPK13MAPK12MAPK11 | |
| SCHEMBL4410021 | 0.88 | MAPK14 (0.70) | MAPK14SCARB1MAPK13MAPK12MAPK11 | |
| SCHEMBL1600560 | 0.87 | MAPK14 (1.00) | MAPK14SCARB1 | |
| SCHEMBL1601028 | 0.87 | MAPK14 (0.86) | MAPK14SCARB1MAPK13MAPK12MAPK11 | |
| Hydrochloric Acid SCHEMBL1899167 | 0.87 | MAPK14 (0.98) | MAPK14SCARB1 | |
| SCHEMBL1602454 | 0.85 | MAPK14 (0.86) | MAPK14SCARB1MAPK13MAPK12MAPK11 | |
| SCHEMBL1902717 | 0.85 | MAPK14 (0.72) | MAPK14SCARB1MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089034-A2 | CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-07-24 | — | — | WO | disclosed |