Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.40 |
| ▸ | PTGFR | P43088 | 2/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.40 |
| ▸ | PTGIR | P43119 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4410113 | 1.00 | MIF (0.61) | MIFEGFRCYP4F2CYP4A11PTGER3 | |
| SCHEMBL4417309 | 0.85 | EGFR (0.64) | MIFEGFRCYP4F2CYP4A11PTGER3 | |
| SCHEMBL4417306 | 0.85 | EGFR (0.64) | MIFEGFRCYP4F2CYP4A11PTGER3 | |
| SCHEMBL6364266 | 0.82 | MIF (0.55) | MIFEGFRCYP4F2CYP4A11PTGER3 | |
| SCHEMBL6166681 | 0.81 | ESR1 (0.50) | MIFEGFRPTGER3PTGER2TBXA2R | |
| SCHEMBL6166674 | 0.81 | ESR1 (0.50) | MIFEGFRPTGER3PTGER2TBXA2R | |
| SCHEMBL13311782 | 0.80 | CYP3A4 (0.46) | MIFCYP4F2CYP4A11CA1CA2 | |
| SCHEMBL3500591 | 0.80 | CYP3A4 (0.46) | MIFCYP4F2CYP4A11CA1CA2 | |
| SCHEMBL1469976 | 0.78 | MIF (0.67) | MIFTDO2EIF2AK2CSNK2A2CSNK2B | |
| SCHEMBL1469977 | 0.78 | MIF (0.67) | MIFTDO2EIF2AK2CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2096109-A1 | CARBOXYLIC ACID DERIVATIVE | Astellas Pharma Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |