Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.64 |
| ▸ | MIF | P14174 | 1/20 | 0.63 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.41 |
| ▸ | PTGFR | P43088 | 2/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.40 |
| ▸ | PTGIR | P43119 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4417309 | 1.00 | EGFR (0.64) | EGFRMIFCYP4F2CYP4A11PTGER3 | |
| SCHEMBL17508763 | 0.87 | EGFR (0.69) | EGFRMIFCYP4F2CYP4A11PTGER3 | |
| SCHEMBL17508764 | 0.87 | EGFR (0.69) | EGFRMIFCYP4F2CYP4A11PTGER3 | |
| SCHEMBL4410110 | 0.85 | MIF (0.61) | EGFRMIFCYP4F2CYP4A11PTGER3 | |
| SCHEMBL4410113 | 0.85 | MIF (0.61) | EGFRMIFCYP4F2CYP4A11PTGER3 | |
| SCHEMBL6364266 | 0.80 | MIF (0.55) | EGFRMIFCYP4F2CYP4A11PTGER3 | |
| SCHEMBL6167022 | 0.80 | EGFR (0.64) | EGFRMIFPTGER3PTGER2TBXA2R | |
| SCHEMBL5893730 | 0.80 | EGFR (0.64) | EGFRMIFPTGER3PTGER2TBXA2R | |
| SCHEMBL6167026 | 0.80 | EGFR (0.64) | EGFRMIFPTGER3PTGER2TBXA2R | |
| SCHEMBL5893724 | 0.80 | EGFR (0.64) | EGFRMIFPTGER3PTGER2TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2096109-A1 | CARBOXYLIC ACID DERIVATIVE | Astellas Pharma Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |