SCHEMBL4410154

SCHEMBL4410154

O=[PH](Oc1cc(Cl)cc(Cl)c1)Oc1cc(Cl)cc(Cl)c1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SOD1 P00441 2/20 0.42
CYP2C19 P33261 1/20 0.42
TSHR P16473 2/20 0.42
MAPT P10636 1/20 0.34
AHR P35869 2/20 0.33
TPMT P51580 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
IDO1 P14902 1/20 0.31
DAO P14920 1/20 0.31
KDM4E B2RXH2 1/20 0.30
GAA P10253 1/20 0.30
PPARG P37231 1/20 0.30
NCOA2 Q15596 1/20 0.30
NCOA1 Q15788 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
NCOA3 Q9Y6Q9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28852091 0.80 TSHR (0.38) SOD1CYP2C19TSHRMAPTTPMT
SCHEMBL11165839 0.77 WDR5 (0.46) CYP2C19TSHRKDM4E
SCHEMBL4408434 0.74 MEN1 (0.43) SOD1CYP2C19MAPTCYP3A4DAO
SCHEMBL4407031 0.69 HSP90AA1 (0.44) TSHRAHRTP53CYP3A4DAO
SCHEMBL6891791 0.68 F2 (0.32) MAPTCYP3A4
SCHEMBL10706723 0.67 TSHR (0.57) SOD1CYP2C19TSHRMAPTAHR
1,3,5-Trichlorobenzene SCHEMBL429512 0.65
SCHEMBL11039151 0.64 TSHR (0.45) CYP2C19TSHRMAPTTP53CYP3A4
SCHEMBL2088495 0.63 TSHR (0.42) SOD1CYP2C19TSHRMAPTTPMT
SCHEMBL2094042 0.63 MAPT (0.48) SOD1CYP2C19TSHRMAPTTPMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7635748-B2 Resin and article molded therefrom TORAY INDUSTRIES, INC. (JP) 2009-12-22 US disclosed
EP-1270646-B1 RESIN COMPOSITION AND ARTICLES MOLDED THEREFROM TORAY INDUSTRIES (JP) 2008-11-26 EP disclosed
US-20080139778-A1 Resin and article molded therefrom TAKANISHI KEIJIRO 2008-06-12 US disclosed
US-20060287464-A1 Resin and article molded therefrom TORAY INDUSTRIES, INC. (JP) 2006-12-21 US disclosed
EP-1640405-A1 RESIN AND ARTICLE MOLDED THEREFROM TORAY INDUSTRIES, INC. (JP) 2006-03-29 EP disclosed
US-6750313-B2 HIGH REFRACTIVE INDEX AND LOW DISPERSION CHARACTERISTICS; OPTICAL LENSES, FILMS, DISCS; POLYCARBONATE RESIN CONTAINING A PHOSPHONIC ACID GROUP TORAY INDUSTRIES, INC. (JP) 2004-06-15 US disclosed
US-20030013836-A1 Resin composition and articles molded therefrom TORAY INDUSTRIES, INC., A CORPORATION OF JAPAN (JP) 2003-01-16 US disclosed
EP-1270646-A1 RESIN COMPOSITION AND ARTICLES MOLDED THEREFROM TORAY INDUSTRIES, INC. (JP) 2003-01-02 EP disclosed