Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3636126 | 0.74 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1TSHRTACR1DDB1 | |
| SCHEMBL3131040 | 0.69 | TSHR (0.41) | ALDH1A1L3MBTL1TSHRGAASMN1; SMN2 | |
| SCHEMBL27331494 | 0.69 | IDO1 (1.00) | IDO1 | |
| SCHEMBL4386224 | 0.68 | IDO1 (0.57) | IDO1TACR1 | |
| SCHEMBL17465795 | 0.68 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1TSHRGAAKDM4E | |
| SCHEMBL28781263 | 0.68 | TSHR (0.44) | ALDH1A1L3MBTL1TSHRGAAKDM4E | |
| SCHEMBL4078370 | 0.67 | TSHR (0.48) | ALDH1A1L3MBTL1TSHRGAAKDM4E | |
| SCHEMBL11604414 | 0.65 | TSHR (0.46) | ALDH1A1L3MBTL1TSHRGAAKDM4E | |
| SCHEMBL26916320 | 0.65 | TSHR (0.46) | ALDH1A1L3MBTL1TSHRGAASMN1; SMN2 | |
| SCHEMBL22011492 | 0.65 | TSHR (0.46) | ALDH1A1L3MBTL1TSHRGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2040698-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008008398-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2008-01-17 | — | — | WO | disclosed |