Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5789731 | 0.81 | — | — | |
| SCHEMBL29913544 | 0.76 | — | — | |
| SCHEMBL1149811 | 0.72 | — | — | |
| SCHEMBL18928641 | 0.62 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL21558248 | 0.62 | PSMB5 (0.54) | ALDH1A1 | |
| SCHEMBL23961741 | 0.61 | SUCNR1 (0.44) | ALDH1A1 | |
| SCHEMBL23008410 | 0.60 | PSMB5 (0.51) | ALDH1A1 | |
| SCHEMBL3192012 | 0.59 | MCL1 (0.43) | ALDH1A1 | |
| SCHEMBL10325567 | 0.58 | — | — | |
| SCHEMBL12443985 | 0.58 | ALDH1A1 (0.46) | HDAC4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2124943-A1 | PYRAZOLO [3, 4-B]PYRIDINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2009-12-02 | — | — | EP | claimed |
| WO-2008111009-A1 | PYRAZOLO [3, 4-B] PYRIDINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2008-09-18 | — | — | WO | claimed |