Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.48 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3965173 | 1.00 | LMNA (0.69) | LMNAKCNH2AADATKDM4ESMN1; SMN2 | |
| SCHEMBL3965168 | 1.00 | LMNA (0.69) | LMNAKCNH2AADATKDM4ESMN1; SMN2 | |
| SCHEMBL3968764 | 0.94 | LMNA (0.73) | LMNAKCNH2AADATKDM4ESMN1; SMN2 | |
| SCHEMBL966483 | 0.94 | LMNA (0.73) | LMNAKCNH2AADATKDM4ESMN1; SMN2 | |
| SCHEMBL3965024 | 0.94 | LMNA (0.73) | LMNAKCNH2AADATKDM4ESMN1; SMN2 | |
| SCHEMBL3968769 | 0.94 | LMNA (0.73) | LMNAKCNH2AADATKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL967999 | 0.93 | LMNA (0.72) | LMNAKCNH2AADATKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3974708 | 0.92 | LMNA (0.69) | LMNAKCNH2AADATKDM4ESMN1; SMN2 | |
| Acetic Acid SCHEMBL3970333 | 0.92 | LMNA (0.71) | LMNAKCNH2AADATKDM4ESMN1; SMN2 | |
| Acetic Acid SCHEMBL3970329 | 0.92 | LMNA (0.71) | LMNAKCNH2AADATKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2030620-A1 | (s)-benzoquinolizine carboxylic acids and their use as antibacterial agents | Wockhardt Limited (IN) | 2009-03-04 | — | — | EP | disclosed |