Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.86 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 6/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11828985 | 0.96 | TSHR (0.86) | TSHRTHRBNAAAPOLBAPEX1 | |
| Butyl Alcohol SCHEMBL17472918 | 0.96 | TSHR (0.86) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL5067997 | 0.96 | TSHR (0.86) | TSHRTHRBNAAAPOLBAPEX1 | |
| Butyl Alcohol SCHEMBL17472910 | 0.95 | TSHR (0.82) | TSHRTHRBNAAAPOLBAPEX1 | |
| Propanol SCHEMBL17472935 | 0.95 | TSHR (0.89) | TSHRTHRBNAAAPOLBAPEX1 | |
| Ethylene Glycol SCHEMBL10600183 | 0.95 | TSHR (0.89) | TSHRTHRBNAAAPOLBAPEX1 | |
| Ethylene Glycol SCHEMBL20263739 | 0.95 | TSHR (0.89) | TSHRTHRBNAAAPOLBAPEX1 | |
| Ethylene Glycol SCHEMBL27514805 | 0.95 | TSHR (0.89) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL11802107 | 0.94 | TSHR (0.75) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL7198622 | 0.93 | TSHR (0.86) | TSHRTHRBNAAAPOLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090317443-A1 | COATED IMPLANT | BIOCOMPATIBLES UK LIMITED CHAPMAN HOUSE (GB) | 2009-12-24 | — | — | US | disclosed |
| WO-2008006911-A1 | COATED IMPLANT | BIOCOMPATIBLES UK LIMITED (GB) | 2008-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090317443-A1 | COATED IMPLANT | ITGA5, ITGB7, ITGA1 | TSHR 4153/4885THRB 4203/4885NAAA 3378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.