SCHEMBL4410907

SCHEMBL4410907

O=C(O)C(CBr)CCBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28475499 0.88 CHRM1 (0.52)
SCHEMBL11633541 0.84 CA2 (0.43)
SCHEMBL348796 0.82
SCHEMBL143441 0.79
SCHEMBL5870378 0.79
SCHEMBL4410902 0.79 CHRM1 (0.44)
SCHEMBL5870376 0.79
SCHEMBL27535823 0.77 CHRM1 (0.76)
SCHEMBL9381886 0.76
SCHEMBL13477877 0.75 CA2 (0.68)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2352721-B1 NOVEL PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES UCB PHARMA GMBH (DE) 2013-03-27 EP claimed
EP-3375771-B1 METHOD FOR PRODUCING LACOSAMIDE AND INTERMEDIATE THEREOF UBE CORP (JP) 2025-11-26 EP disclosed
US-11623943-B2 Method for producing lacosamide and intermediate thereof API CORPORATION (JP) 2023-04-11 US disclosed
US-20210188904-A1 METHOD FOR PRODUCING LACOSAMIDE AND INTERMEDIATE THEREOF API CORPORATION (JP) 2021-06-24 US disclosed
US-10975117-B2 Method for producing lacosamide and intermediate thereof API CORPORATION (JP) 2021-04-13 US disclosed
EP-3659997-A1 METHOD FOR PRODUCING LACOSAMIDE AND INTERMEDIATE THEREOF API Corporation (JP) 2020-06-03 EP disclosed
US-20180371013-A1 METHOD FOR PRODUCING LACOSAMIDE AND INTERMEDIATE THEREOF API CORPORATION (JP) 2018-12-27 US disclosed
EP-3375771-A1 METHOD FOR PRODUCING LACOSAMIDE AND INTERMEDIATE THEREOF API Corporation (JP) 2018-09-19 EP disclosed
US-8344181-B2 Obesity, type 2 diabetes, hyperlipidemia, hypertension, arteriosclerosis, coronary heart diseases JANSSEN PHARMACEUTICA N.V. (BE) 2013-01-01 US disclosed
CN-1930137-B Benzothiazepine and benzoazepine compounds ASAHI KASEI PHARMA CORP 2011-07-20 CN disclosed
WO-2006024627-A9 N-2 ADAMANTANYL-2-PHENOXY-ACETAMIDE DERIVATIVES AS 11-BETA HYDROXYSTEROID DEHYDROGENASE INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2008-02-14 WO disclosed
EP-1796657-A2 N-2 ADAMANTANYL-2-PHENOXY-ACETAMIDE DERIVATIVES AS 11-BETA HYDROXYSTEROID DEHYDROGENASE INHIBITORS JANSSEN PHARMACEUTICA N.V. (BE) 2007-06-20 EP disclosed
WO-2006024627-A2 N-2 ADAMANTANYL-2-PHENOXY-ACETAMIDE DERIVATIVES AS 11-BETA HYDROXYSTEROID DEHYDROGENASE INHIBITORS JANSSEN PHARMACEUTICA N.V. (BE) 2006-03-09 WO disclosed
CN-1724532-A Colorant compound XEROX CORP (US) 2006-01-25 CN disclosed
CN-1724597-A Phase change inks XEROX CORP (US) 2006-01-25 CN disclosed
CN-1046524-C Cephalosporin derivatives HOFFMANN LA ROCHE (CH) 1999-11-17 CN disclosed
CN-1171400-A Xantone compounds, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1998-01-28 CN disclosed
CN-1105365-A Cephalosporin derivatives HOFFMANN LA ROCHE (CH) 1995-07-19 CN disclosed
CN-1019387-B PROCESS FOR PREPN. OF PROPANOL DERIVATIVES SYN TEK AB (SE) 1992-12-09 CN disclosed
CN-86100170-A The preparation method of propanol derivative 1986-12-17 CN disclosed