Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.52 |
| ▸ | CNR2 | P34972 | 6/20 | 0.42 |
| ▸ | CNR1 | P21554 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4410926 | 1.00 | PPARA (0.52) | PPARACNR2CNR1PPARGPPARD | |
| SCHEMBL16949679 | 0.85 | ALDH1A1 (0.57) | PPARACNR2CNR1PPARGALDH1A1 | |
| SCHEMBL26624583 | 0.85 | ALDH1A1 (0.57) | PPARACNR2CNR1PPARGALDH1A1 | |
| SCHEMBL5744794 | 0.85 | ALDH1A1 (0.57) | PPARACNR2CNR1PPARGALDH1A1 | |
| SCHEMBL16949678 | 0.85 | ALDH1A1 (0.57) | PPARACNR2CNR1PPARGALDH1A1 | |
| SCHEMBL5744792 | 0.85 | ALDH1A1 (0.57) | PPARACNR2CNR1PPARGALDH1A1 | |
| SCHEMBL16831513 | 0.85 | TSHR (0.42) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL16057346 | 0.85 | TSHR (0.42) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL689833 | 0.85 | TSHR (0.42) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL30239801 | 0.83 | ALDH1A1 (0.55) | PPARACNR2CNR1PPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635765-B2 | Nucleotide sequences coding polypeptide for use in generation of preferential antibiotics; polynucleotide which encodes a domain of a ramoplanin nonribosomal peptide synthetase | THALLION PHARMACEUTICALS, INC. (CA) | 2009-12-22 | — | — | US | disclosed |
| US-7078185-B2 | Gene encoding a nonribosomal peptide synthetase for the production of ramoplanin | ECOPIA BIOSCIENCES INC. (CA) | 2006-07-18 | — | — | US | disclosed |
| US-20050287641-A1 | Nucleotide sequences coding polypeptide for use in generation of preferential antibiotics; polynucleotide which encodes a domain of a ramoplanin nonribosomal peptide synthetase | ECOPIA BIOSCIENCES, INC. | 2005-12-29 | — | — | US | disclosed |
| EP-1326983-B1 | GENE CLUSTER FOR RAMOPLANIN BIOSYNTHESIS | ECOPIA BIOSCIENCES INC (CA) | 2005-04-06 | — | — | EP | disclosed |
| EP-1326983-A2 | GENE CLUSTER FOR RAMOPLANIN BIOSYNTHESIS | Ecopia Biosciences Inc. (CA) | 2003-07-16 | — | — | EP | disclosed |
| US-20020164747-A1 | Gene cluster for ramoplanin biosynthesis | ECOPIA BIOSCIENCES INC. | 2002-11-07 | — | — | US | disclosed |
| WO-2002031155-A2 | GENE CLUSTER FOR RAMOPLANIN BIOSYNTHESIS | ECOPIA BIOSCIENCES INC. (CA) | 2002-04-18 | — | — | WO | disclosed |