Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.55 |
| ▸ | HPGD | P15428 | 10/20 | 0.55 |
| ▸ | GAA | P10253 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4125207 | 0.97 | KDM4E (0.53) | KDM4EALDH1A1HPGDGAANPC1 | |
| SCHEMBL4413498 | 0.95 | KDM4E (0.52) | KDM4EALDH1A1HPGDGAANPC1 | |
| SCHEMBL12057603 | 0.73 | MAPT (0.36) | KDM4EALDH1A1HPGDGAANPC1 | |
| SCHEMBL28116388 | 0.73 | SMN1; SMN2 (0.73) | ALDH1A1HPGDNPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL24256901 | 0.72 | KDM4E (0.77) | KDM4EALDH1A1HPGDGAANPC1 | |
| SCHEMBL5548523 | 0.68 | KDM4E (0.50) | KDM4EALDH1A1HPGDGAANPC1 | |
| SCHEMBL23530696 | 0.68 | SMN1; SMN2 (0.52) | KDM4EALDH1A1HPGDGAANPC1 | |
| SCHEMBL23530446 | 0.68 | SMN1; SMN2 (0.52) | KDM4EALDH1A1HPGDNPC1SMN1; SMN2 | |
| SCHEMBL264016 | 0.67 | KDM4E (0.49) | KDM4EALDH1A1HPGDGAANPC1 | |
| SCHEMBL526385 | 0.67 | BRD4 (0.48) | KDM4EALDH1A1HPGDGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009056551-A1 | FURO[3,2-D]PYRIMIDINE DERIVATIVES | PALAU PHARMA, S. A. (ES) | 2009-05-07 | — | — | WO | disclosed |