Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4125207 | 0.98 | KDM4E (0.53) | KDM4EMAPTMAPK1HTTALDH1A1 | |
| SCHEMBL4411095 | 0.95 | KDM4E (0.55) | KDM4EMAPTMAPK1HTTALDH1A1 | |
| SCHEMBL12057603 | 0.75 | MAPT (0.36) | KDM4EMAPTMAPK1HTTALDH1A1 | |
| SCHEMBL28116388 | 0.69 | SMN1; SMN2 (0.73) | MAPTALDH1A1HPGDCYP1A2NPC1 | |
| SCHEMBL24256901 | 0.68 | KDM4E (0.77) | KDM4EMAPTMAPK1HTTALDH1A1 | |
| SCHEMBL13151524 | 0.68 | MAPT (0.64) | KDM4EMAPTHTTALDH1A1HPGD | |
| SCHEMBL5548523 | 0.67 | KDM4E (0.50) | KDM4EMAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL14079850 | 0.67 | ALDH1A1 (0.46) | KDM4EMAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL2289470 | 0.67 | ALDH1A1 (0.45) | KDM4EMAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL2803645 | 0.67 | ALDH1A1 (0.65) | KDM4EMAPTMAPK1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009056551-A1 | FURO[3,2-D]PYRIMIDINE DERIVATIVES | PALAU PHARMA, S. A. (ES) | 2009-05-07 | — | — | WO | disclosed |