Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 9/20 | 0.76 |
| ▸ | CD274 | Q9NZQ7 | 9/20 | 0.76 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.65 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.65 |
| ▸ | TUBB | P07437 | 2/20 | 0.65 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.65 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.65 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.65 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.65 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.65 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.65 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.65 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.65 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.65 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.65 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.65 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4411377 | 1.00 | PDCD1 (0.76) | PDCD1CD274TUBB1TUBB4ATUBB | |
| SCHEMBL9085876 | 0.97 | PDCD1 (0.72) | PDCD1CD274TUBB1TUBB4ATUBB | |
| SCHEMBL9085864 | 0.97 | PDCD1 (0.72) | PDCD1CD274TUBB1TUBB4ATUBB | |
| SCHEMBL13991619 | 0.94 | PDCD1 (0.68) | PDCD1CD274TUBB1TUBB4ATUBB | |
| SCHEMBL9587052 | 0.93 | CYP1A1 (0.65) | PDCD1CD274HDAC3HDAC4HDAC1 | |
| SCHEMBL9587050 | 0.93 | CYP1A1 (0.65) | PDCD1CD274HDAC3HDAC4HDAC1 | |
| SCHEMBL23671611 | 0.92 | PDCD1 (0.66) | PDCD1CD274TUBB1TUBB4ATUBB | |
| SCHEMBL23671612 | 0.92 | PDCD1 (0.66) | PDCD1CD274TUBB1TUBB4ATUBB | |
| SCHEMBL20693103 | 0.89 | PDCD1 (0.62) | PDCD1CD274TUBB1TUBB4ATUBB | |
| SCHEMBL20693104 | 0.89 | PDCD1 (0.62) | PDCD1CD274TUBB1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11279678-B2 | 5-fluorouracil derivatives, preparation methods and uses thereof | SHANGHAI ECUST BIOMEDICINE CO., LTD. (CN) | 2022-03-22 | — | — | US | disclosed |
| US-20210230122-A1 | 5-FLUOROURACIL DERIVATIVES, PREPARATION METHODS AND USES THEREOF | SHANGHAI ECUST BIOMEDICINE CO., LTD. (CN) | 2021-07-29 | — | — | US | disclosed |
| CN-106336347-B | New method for synthesizing hydroxystilbenes | 中国科学院成都有机化学有限公司 | 2020-08-18 | — | — | CN | disclosed |
| US-7632863-B2 | 3,4,5,4′-tetramethoxyl-α,β-diphenylethane-3′-O-sodium sulphate and its use | THE JIAN CELL BIOMEDICAL RESEARCH CO., LTD. (CN) | 2009-12-15 | — | — | US | disclosed |
| US-20080234369-A1 | 3,4,5,4' - TETRAMETHOXYL- ALPHA,BETA-DIPHENYLETHANE -3' -0- SODIUMSULPHATE AND ITS USE | THE JIANG CELL BIOMEDICAL RESEARCH CO., LTD. (CN) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234369-A1 | 3,4,5,4' - TETRAMETHOXYL- ALPHA,BETA-DIPHENYLETHANE -3' -0- SODIUMSULPHATE AND ITS USE | SULT1E1, EBP, SULT1A1 | PDCD1 3107/4885CD274 3653/4885TUBB1 111/4885 |
| US-11279678-B2 | 5-fluorouracil derivatives, preparation methods and uses thereof | VEGFA, FLT4, FAU | PDCD1 2799/4885CD274 2650/4885TUBB1 310/4885 |
| US-20210230122-A1 | 5-FLUOROURACIL DERIVATIVES, PREPARATION METHODS AND USES THEREOF | VEGFA, FLT4, FAU | PDCD1 2799/4885CD274 2650/4885TUBB1 310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.