Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.78 |
| ▸ | DPP8 | Q6V1X1 | 15/20 | 0.78 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.66 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.66 |
| ▸ | FAP | Q12884 | 1/20 | 0.58 |
| ▸ | PREP | P48147 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3554780 | 0.88 | DPP4 (1.00) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL3554784 | 0.88 | DPP4 (1.00) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL14392573 | 0.88 | DPP4 (1.00) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL4422815 | 0.87 | DPP4 (0.68) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL4419185 | 0.80 | DPP4 (0.73) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL6453066 | 0.80 | DPP4 (1.00) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL14392585 | 0.80 | DPP4 (0.78) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL14392722 | 0.79 | DPP4 (1.00) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL4415874 | 0.78 | DPP4 (0.89) | DPP4DPP8DPP7PREP | |
| SCHEMBL3549522 | 0.78 | DPP4 (1.00) | DPP4DPP8DPP7DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1729774-A4 | PYRROLIDINE COMPOUNDS | NAT HEALTH RESEARCH INSTITUTES (TW) | 2009-05-06 | — | — | EP | claimed |
| EP-1729774-A1 | PYRROLIDINE COMPOUNDS | National Health Research Institutes (TW) | 2006-12-13 | — | — | EP | claimed |
| WO-2005087235-A1 | PYRROLIDINE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (CN) | 2005-09-22 | — | — | WO | claimed |
| EP-1729774-A4 | PYRROLIDINE COMPOUNDS | NAT HEALTH RESEARCH INSTITUTES (TW) | 2009-05-06 | — | — | EP | disclosed |
| EP-1729774-A1 | PYRROLIDINE COMPOUNDS | National Health Research Institutes (TW) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005087235-A1 | PYRROLIDINE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (CN) | 2005-09-22 | — | — | WO | disclosed |