SCHEMBL4412166

SCHEMBL4412166

CC1(C)CCC(C)(C)c2cc3c(cc21)CC(=O)C3

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.37
RXRA P19793 14/20 0.37
RXRB P28702 11/20 0.37
RARB P10826 9/20 0.37
RXRG P48443 8/20 0.37
RARG P13631 8/20 0.37
CYP26A1 O43174 3/20 0.36
CYP26B1 Q9NR63 2/20 0.36
RARA P10276 7/20 0.35
CYP3A4 P08684 1/20 0.34
CRABP2 P29373 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5009416 0.76 RXRA (0.41) RXRARXRBRARBRXRGRARG
SCHEMBL29401105 0.76 RXRA (0.41) RXRARXRBRARBRXRGRARG
Lithium SCHEMBL29602414 0.74 RXRA (0.40) RXRARXRBRARBRXRGRARG
SCHEMBL11599145 0.74 RXRA (0.42) CYP1A2RXRARXRBRARBRXRG
SCHEMBL8308767 0.71 RXRA (0.36) RXRARXRBRARBRXRGRARG
SCHEMBL6939291 0.71 RXRA (0.36) RXRARXRBRARBRXRGRARG
SCHEMBL7624438 0.71 PBRM1 (0.44) RXRARXRBRARBRXRGRARG
SCHEMBL3061673 0.70 RXRA (0.39) RXRARXRBRARBRXRGRARG
SCHEMBL6916096 0.69 CA9 (0.50)
SCHEMBL6915238 0.69 MEN1 (0.51)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7601666-B2 Provide polymers having high molecular weight as well as good crystallinity preferably prepared at higher temperatures and productivities than otherwise possible EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-10-13 US disclosed
EP-1765841-B1 OLEFIN POLYMERIZATION CATALYST SYSTEM AND PROCESS FOR USE THEREOF EXXONMOBIL CHEM PATENTS INC (US) 2008-10-08 EP disclosed
US-20060009595-A1 Olefin polymerization catalyst system and process for use thereof EXXONMOBIL CHEMICAL PATENTS INC. 2006-01-12 US disclosed
EP-1157047-B1 LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS BP CORP NORTH AMERICA INC (US) 2003-04-23 EP disclosed
US-6479424-B1 FOR PRODUCING OLEFIN POLYMERS AND ESPECIALLY ELASTOMERIC PROPYLENE POLYMERS BP CORPORATION NORTH AMERICA INC. 2002-11-12 US disclosed
EP-1157047-A1 LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS BP Corporation North America Inc. (US) 2001-11-28 EP disclosed
WO-2000035975-A1 LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS BP CORPORATION NORTH AMERICA INC. (US) 2000-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060009595-A1 Olefin polymerization catalyst system and process for use thereof OR10J3, CHRM2, CHRM1 CYP1A2 623/4885RXRA 1309/4885RXRB 1474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.