Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.60 |
| ▸ | ACE | P12821 | 3/20 | 0.56 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.55 |
| ▸ | NMBR | P28336 | 5/20 | 0.54 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.54 |
| ▸ | ECE1 | P42892 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | IL1RN | P18510 | 1/20 | 0.53 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4410184 | 1.00 | ERAP2 (0.60) | ERAP2ACESIRT5NMBRKCNA5 | |
| SCHEMBL4612012 | 0.91 | KCNA5 (0.63) | ACENMBRKCNA5ECE1MEN1 | |
| SCHEMBL8785114 | 0.91 | KCNA5 (0.63) | ACENMBRKCNA5ECE1MEN1 | |
| SCHEMBL3820631 | 0.91 | KCNA5 (0.63) | ACENMBRKCNA5ECE1MEN1 | |
| Glycine SCHEMBL28118897 | 0.88 | NMBR (0.60) | ACENMBRKCNA5ECE1MEN1 | |
| Glycine SCHEMBL28118895 | 0.88 | NMBR (0.60) | ACENMBRKCNA5ECE1MEN1 | |
| SCHEMBL27462136 | 0.86 | ERAP2 (0.60) | ERAP2ACEECE1MEN1KMT2A | |
| SCHEMBL27462135 | 0.86 | ERAP2 (0.60) | ERAP2ACEECE1MEN1KMT2A | |
| SCHEMBL4419904 | 0.86 | PPARG (0.54) | ERAP2ACENMBRKCNA5MEN1 | |
| Pyridine SCHEMBL27529532 | 0.85 | KCNA5 (0.58) | ACENMBRKCNA5ECE1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121728-A1 | CRYSTALLINE D-ISOGLUTAMYL-D-TRYPTOPHAN AND THE MONO AMMONIUM SALT OF D-ISOGLUTAMYL- D-TRYPTOPHAN | Apotex Technologies Inc. (CA) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008064465-A1 | CRYSTALLINE D-ISOGLUTAMYL-D-TRYPTOPHAN AND THE MONO AMMONIUM SALT OF D-ISOGLUTAMYL- D-TRYPTOPHAN | APOTEX TECHNOLOGIES INC. (CA) | 2008-06-05 | — | — | WO | disclosed |