Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 2/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | ACE | P12821 | 3/20 | 0.61 |
| ▸ | NMBR | P28336 | 5/20 | 0.60 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.59 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.59 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.59 |
| ▸ | ITGAL | P20701 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ECE1 | P42892 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8785114 | 1.00 | KCNA5 (0.63) | KCNA5ALOX15ACENMBRP2RY14 | |
| SCHEMBL3820631 | 1.00 | KCNA5 (0.63) | KCNA5ALOX15ACENMBRP2RY14 | |
| Glycine SCHEMBL28118895 | 0.95 | NMBR (0.60) | KCNA5ALOX15ACENMBRP2RY14 | |
| Glycine SCHEMBL28118897 | 0.95 | NMBR (0.60) | KCNA5ALOX15ACENMBRP2RY14 | |
| Pyridine SCHEMBL27529532 | 0.94 | KCNA5 (0.58) | KCNA5ALOX15ACENMBRP2RY14 | |
| SCHEMBL8547809 | 0.91 | KMT2A (0.66) | KCNA5NMBRKMT2AMEN1 | |
| SCHEMBL4410184 | 0.91 | ERAP2 (0.60) | KCNA5ACENMBRKMT2AMEN1 | |
| SCHEMBL4412285 | 0.91 | ERAP2 (0.60) | KCNA5ACENMBRKMT2AMEN1 | |
| SCHEMBL12017025 | 0.89 | NMBR (0.61) | ALOX15ACENMBRITGB2ICAM1 | |
| SCHEMBL4419904 | 0.89 | PPARG (0.54) | KCNA5ALOX15ACENMBRP2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3429354-A1 | B-VITAMIN AND AMINO ACID CONJUGATES OF NICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, DERIVATIVES THEREOF, AND METHODS OF PREPARATION THEREOF | Chromadex Inc. (US) | 2019-01-23 | — | — | EP | claimed |
| WO-2017161165-A1 | B-VITAMIN AND AMINO ACID CONJUGATES OF NICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, DERIVATIVES THEREOF, AND METHODS OF PREPARATION THEREOF | ChromaDex Inc. (US) | 2017-09-21 | — | — | WO | claimed |
| CN-109438321-A | A kind of tryptophan derivative and its preparation method and application | 南京友怡医药科技有限公司 | 2019-03-08 | — | — | CN | disclosed |
| CN-106478771-A | A kind of synthetic method of amino acid neural tetrapeptide | 李世军 | 2017-03-08 | — | — | CN | disclosed |
| CN-106279354-A | A kind of synthetic method of amino acid neural dipeptides | 温州医科大学 | 2017-01-04 | — | — | CN | disclosed |
| CN-101932560-A | Matrix metalloproteinase inhibitors, pharmaceutical compositions containing them and their use | POISON MED INST PLA MED ACAD | 2010-12-29 | — | — | CN | disclosed |
| WO-2008080223-A1 | COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE DISEASE | MIGENIX INC. (CA) | 2008-07-10 | — | — | WO | disclosed |
| EP-1910279-A2 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2008-04-16 | — | — | EP | disclosed |
| US-7163671-B2 | Long-term stabilized formulations | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2007-01-16 | — | — | US | disclosed |
| WO-2007002639-A2 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2007-01-04 | — | — | WO | disclosed |
| US-20030092622-A1 | Preparation stabilized over long time | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-05-15 | — | — | US | disclosed |
| EP-1260230-A1 | PREPARATIONS STABILIZED OVER LONG TIME | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-11-27 | — | — | EP | disclosed |
| EP-0994712-A1 | INHIBITORS OF NEUTROPHIL MEDIATED OXIDANT PRODUCTION | ELI LILLY AND COMPANY (US) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999002163-A1 | INHIBITORS OF NEUTROPHIL MEDIATED OXIDANT PRODUCTION | ELI LILLY AND COMPANY (US) | 1999-01-21 | — | — | WO | disclosed |
| EP-0807114-A1 | BRIDGED INDOLES AS MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1997-11-19 | — | — | EP | disclosed |