Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2841930 | 0.84 | HPGD (0.46) | HSD11B1RAB9AHPGDCYP1A2CYP2C9 | |
| SCHEMBL2841931 | 0.84 | HPGD (0.46) | HSD11B1RAB9AHPGDCYP1A2CYP2C9 | |
| SCHEMBL12324931 | 0.82 | GPR119 (0.47) | L3MBTL1GPR119USP30 | |
| SCHEMBL4408401 | 0.80 | KMT2A (0.42) | MEN1KMT2A | |
| SCHEMBL4409429 | 0.80 | KLK5 (0.40) | L3MBTL1GPR119BCHEKMT2ATSHR | |
| SCHEMBL29997863 | 0.78 | KLK7 (0.45) | L3MBTL1GPR119CYP2C9HSD17B10MEN1 | |
| SCHEMBL1843454 | 0.78 | KLK7 (0.45) | L3MBTL1GPR119CYP2C9HSD17B10MEN1 | |
| SCHEMBL28194949 | 0.78 | KLK7 (0.45) | L3MBTL1GPR119CYP2C9HSD17B10MEN1 | |
| SCHEMBL13997813 | 0.78 | KLK7 (0.45) | L3MBTL1GPR119CYP2C9HSD17B10MEN1 | |
| SCHEMBL24928632 | 0.78 | EPHX2 (0.42) | L3MBTL1MEN1KMT2AKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7608577-B2 | Peptidyl ketones as inhibitors of DPIV | OSI PHARMACEUTICALS, INC. (US) | 2009-10-27 | — | — | US | disclosed |
| US-5547978-A | ENDOPEPTIDASE INHIBITORS | MEIJI SEIKA KAISHA, LTD. (JP) | 1996-08-20 | — | — | US | disclosed |