Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 8/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PKLR | P30613 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4412445 | 0.83 | HTR6 (0.48) | HTR6PKMHTTTSHRMEN1 | |
| SCHEMBL1996812 | 0.82 | HTR6 (0.48) | HTR6PKMHTTTSHRMEN1 | |
| SCHEMBL2003562 | 0.77 | HTR6 (0.48) | HTR6PKMHTTMEN1KMT2A | |
| SCHEMBL4413034 | 0.73 | HTR6 (0.43) | HTR6 | |
| SCHEMBL2001433 | 0.73 | HTR6 (0.46) | HTR6PKMHTTLMNAPKLR | |
| SCHEMBL1997112 | 0.73 | HTR6 (0.46) | HTR6PKMHTTTSHRPKLR | |
| SCHEMBL1997011 | 0.72 | HTR6 (0.45) | HTR6PKMHTTMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL1996217 | 0.71 | HTR6 (0.42) | HTR6PKMHTTPKLR | |
| SCHEMBL1995180 | 0.70 | HTR6 (0.43) | HTR6PKMHTTPKLR | |
| SCHEMBL1993753 | 0.70 | HTR6 (0.43) | HTR6PKMHTTPKLR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091953-A1 | 8-SULFONYL-L, 3, 4, 8-TETRAHYDR0-2H- [1, 4]OXAZEPINO [6, 7-E]INDOLE DERIVATIVES AND THEIR USE AS 5-HT6 RECEPTOR LIGANDS | BIOVITRUM AB (publ) (SE) | 2009-08-26 | — | — | EP | disclosed |
| WO-2008054288-A1 | 8-SULFONYL-L, 3, 4, 8-TETRAHYDR0-2H- [1, 4] OXAZEPINO [6, 7-E] INDOLE DERIVATIVES AND THEIR USE AS 5-HT6 RECEPTOR LIGANDS | BIOVITRUM AB (PUBL) (SE) | 2008-05-08 | — | — | WO | disclosed |