Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 18/20 | 0.47 |
| ▸ | TACR2 | P21452 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL412095 | 0.90 | CNR1 (0.55) | CNR1TACR2CNR2 | |
| SCHEMBL442344 | 0.86 | CNR1 (0.51) | CNR1CNR2 | |
| SCHEMBL411182 | 0.85 | CNR1 (0.47) | CNR1TACR2CNR2 | |
| SCHEMBL411613 | 0.84 | CNR1 (0.61) | CNR1TACR2LMNACNR2 | |
| SCHEMBL412321 | 0.82 | BCL9 (0.48) | CNR1CNR2 | |
| SCHEMBL444586 | 0.81 | CNR1 (0.45) | CNR1TACR2CNR2 | |
| SCHEMBL412122 | 0.81 | CNR1 (0.45) | CNR1TACR2CNR2 | |
| SCHEMBL412098 | 0.81 | CNR1 (0.45) | CNR1CNR2 | |
| SCHEMBL411171 | 0.81 | CNR1 (0.45) | CNR1CNR2 | |
| SCHEMBL411092 | 0.79 | CNR1 (0.55) | CNR1TACR2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065212-A1 | HETEROARYLMETHYL AMIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-03-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065212-A1 | HETEROARYLMETHYL AMIDES | APOB, LDLR, HMGCR | CNR1 269/4885TACR2 1840/4885LMNA 886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.