⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11799 | 1.00 | — | — | |
| SCHEMBL178952 | 1.00 | — | — | |
| Ethane SCHEMBL27625986 | 0.96 | TSHR (0.41) | — | |
| Methyl Alcohol SCHEMBL27464623 | 0.96 | TSHR (0.41) | — | |
| SCHEMBL2612208 | 0.90 | TSHR (0.37) | — | |
| Propane SCHEMBL28218331 | 0.90 | SHBG (0.46) | — | |
| SCHEMBL16248250 | 0.90 | TSHR (0.37) | — | |
| SCHEMBL14318801 | 0.90 | TSHR (0.37) | — | |
| SCHEMBL1006983 | 0.87 | — | — | |
| SCHEMBL4847697 | 0.87 | TSHR (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102477014-B | The preparation method of Peremin | SHANDONG NEW TIME PHARMACEUTICAL Co.,Ltd. (CN) | 2015-08-19 | — | — | CN | claimed |
| CN-102477014-A | Preparation method of histamine dihydrochloride | SHANGDONG NEW TIME PHARM PROD | 2012-05-30 | — | — | CN | claimed |
| WO-2025125665-A1 | FURTHER SUBSTITUTED IMIDAZOLES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2025-06-19 | — | — | WO | disclosed |
| CN-119767902-A | Color conversion film, light-emitting device and preparation method of light-emitting device | 广东聚华印刷显示技术有限公司 | 2025-04-04 | — | — | CN | disclosed |
| US-20240410055-A1 | METHOD AND FORMULATION FOR PREPARING OPTICAL METAL OXIDE LAYERS | MERCK PATENT GMBH (DE) | 2024-12-12 | — | — | US | disclosed |
| US-20240239790-A1 | 7-Morpholino-1,6-Naphthyridin-5-yl Derivatives and Pharmaceutical Compositions Thereof Useful as DNA-PK Inhibitor | LIFEARC (GB) | 2024-07-18 | — | — | US | disclosed |
| WO-2024148087-A1 | CDK2 INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2024148091-A1 | CDK2 INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2024-07-11 | — | — | WO | disclosed |
| CN-118076767-A | Method and formulation for producing an optical metal oxide layer | 默克专利有限公司 | 2024-05-24 | — | — | CN | disclosed |
| US-20230322791-A1 | CDK2 INHIBITORS | BLUEPRINT MEDICINES CORPORATION | 2023-10-12 | — | — | US | disclosed |
| US-11780851-B2 | LRRK2 inhibitors | H. LUNDBECK A/S (DK) | 2023-10-10 | — | — | US | disclosed |
| WO-2002024663-A2 | PYRIMIDINE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-03-28 | — | — | WO | disclosed |
| US-5298609-A | Light stable yellow pigments for polyolefins | CIBA-GEIGY CORPORATION (US) | 1994-03-29 | — | — | US | disclosed |
| EP-0523005-A2 | Disazodyes with cycloalkylester or cycloalkylamide rests | CIBA-GEIGY AG (CH) | 1993-01-13 | — | — | EP | disclosed |
| US-4816452-A | ANTIBIOTICS | BEECHAM GROUP P.L.C. (GB) | 1989-03-28 | — | — | US | disclosed |
| EP-0100906-B1 | TRI- AND TETRACYCLIC IMIDAZO(1,5-A)(1,4)BENZODIAZEPIN-1-CARBOXYLIC-ACID DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1987-05-13 | — | — | EP | disclosed |
| EP-0210815-A2 | 6-Beta-(alpha-etherified oxyimino)-acylamino penicillanic-acid derivatives, their preparation and use | BEECHAM GROUP PLC (GB) | 1987-02-04 | — | — | EP | disclosed |
| US-4489003-A | ANTICONVULSANTS, TRANQUILLIZERS | HOFFMANN-LA ROCHE INC. (US) | 1984-12-18 | — | — | US | disclosed |
| EP-0100906-A2 | Tri- and tetracyclic imidazo(1,5-a)(1,4)benzodiazepin-1-carboxylic-acid derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-02-22 | — | — | EP | disclosed |
| US-4290961-A | Process for catalytically reducing carbonyl compounds | MONTEDISON S.P.A. (IT) | 1981-09-22 | — | — | US | disclosed |