⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5401146 | 1.00 | — | — | |
| SCHEMBL1296590 | 0.96 | TSHR (0.30) | — | |
| SCHEMBL30722302 | 0.96 | TSHR (0.30) | — | |
| SCHEMBL4419723 | 0.96 | TSHR (0.30) | — | |
| SCHEMBL29859441 | 0.92 | TSHR (0.35) | — | |
| SCHEMBL27756433 | 0.69 | — | — | |
| SCHEMBL13182148 | 0.69 | — | — | |
| SCHEMBL11038684 | 0.69 | — | — | |
| SCHEMBL20027402 | 0.69 | TSHR (0.35) | — | |
| SCHEMBL21903317 | 0.69 | TSHR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7608730-B2 | Process for the preparation of an anti-tumor platinum (II)—complex | FRESENIUS KABI ONCOLOGY LIMITED (IN) | 2009-10-27 | — | — | US | disclosed |
| US-7608730-B2 | Process for the preparation of an anti-tumor platinum (II)—complex | FRESENIUS KABI ONCOLOGY LIMITED (IN) | 2009-10-27 | — | — | US | disclosed |
| US-20080207935-A1 | Process for the Preparation of an Anti-Tumor Platinum (II) - Complex | DABUR RESEARCH FOUNDATION (IN) | 2008-08-28 | — | — | US | disclosed |
| US-20080207935-A1 | Process for the Preparation of an Anti-Tumor Platinum (II) - Complex | DABUR RESEARCH FOUNDATION (IN) | 2008-08-28 | — | — | US | disclosed |
| EP-1749015-A1 | A PROCESS FOR THE PREPARATION OF AN ANTI-TUMOR PLATINUM(II)-COMPLEX | DABUR PHARMA LTD. (IN) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005075489-A1 | A PROCESS FOR THE PERPARATION OF AN ANTI-TUMOR PLATINUM (II) - COMPLEX | DABUR PHARMA LIMITED (IN) | 2005-08-18 | — | — | WO | disclosed |
| US-4256652-A | ANTITUMOR AGENTS | Kidani, Yoshinori (JP) | 1981-03-17 | — | — | US | disclosed |
| EP-0001126-A1 | Cis-platinum (II) complexes of 1,2-diamino-cyclohexane and pharmaceutical composition containing them | Kidani, Yoshinori (JP) | 1979-03-21 | — | — | EP | disclosed |