⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4413431 | 1.00 | — | — | |
| SCHEMBL1296590 | 0.96 | TSHR (0.30) | — | |
| SCHEMBL30722302 | 0.96 | TSHR (0.30) | — | |
| SCHEMBL4419723 | 0.96 | TSHR (0.30) | — | |
| SCHEMBL29859441 | 0.92 | TSHR (0.35) | — | |
| SCHEMBL27756433 | 0.69 | — | — | |
| SCHEMBL13182148 | 0.69 | — | — | |
| SCHEMBL11038684 | 0.69 | — | — | |
| SCHEMBL20027402 | 0.69 | TSHR (0.35) | — | |
| SCHEMBL21903317 | 0.69 | TSHR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208616-B2 | Cis-diiodo-(trans-L-1,2-cyclohexanediamine) platinum (II) complex and processes for preparing high purity oxaliplatin | SICOR, INC. (US) | 2007-04-24 | — | — | US | claimed |
| EP-1658300-A1 | CIS-DIIODO- (TRANS-L-1,2-CYCLOHEXANEDIAMINE) PLATINUM (II) COMPLEX AND PROCESSES FOR PREPARING HIGH PURITY OXALIPLATIN | Sicor Inc. (US) | 2006-05-24 | — | — | EP | claimed |
| WO-2006023154-A1 | CIS-DIIODO- (TRANS-L-1,2-CYCLOHEXANEDIAMINE) PLATINUM (II) COMPLEX AND PROCESSES FOR PREPARING HIGH PURITY OXALIPLATIN | SICOR, INC. (US) | 2006-03-02 | — | — | WO | claimed |
| US-20060041012-A1 | Cis-diiodo-(trans-l-1,2-cyclohexanediamine) platinum (II) complex and processes for preparing high purity oxaliplatin | SICOR, INC. | 2006-02-23 | — | — | US | claimed |
| US-9650403-B2 | Platinum (II) compound, preparation method therefor, and pharmaceutical composition and application thereof | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2017-05-16 | — | — | US | disclosed |
| US-20160194345-A1 | PLATINUM (II) COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2016-07-07 | — | — | US | disclosed |
| CN-101027313-A | Cis-diiodo-(trans-L-1,2-cyclohexanediamine) platinum (II) complex and processes for preparing high purity oxaliplatin | SICOR INC (US) | 2007-08-29 | — | — | CN | disclosed |
| US-20070197811-A1 | Cis-diiodo-(trans-L-1,2-cyclohexanediamine) platinum (II) complex and processes for preparing high purity oxaliplatin | MENEZ GUILLERMO H | 2007-08-23 | — | — | US | disclosed |
| US-20070197811-A1 | Cis-diiodo-(trans-L-1,2-cyclohexanediamine) platinum (II) complex and processes for preparing high purity oxaliplatin | MENEZ GUILLERMO H | 2007-08-23 | — | — | US | disclosed |
| US-7208616-B2 | Cis-diiodo-(trans-L-1,2-cyclohexanediamine) platinum (II) complex and processes for preparing high purity oxaliplatin | SICOR, INC. (US) | 2007-04-24 | — | — | US | disclosed |
| US-7208616-B2 | Cis-diiodo-(trans-L-1,2-cyclohexanediamine) platinum (II) complex and processes for preparing high purity oxaliplatin | SICOR, INC. (US) | 2007-04-24 | — | — | US | disclosed |
| EP-1658300-A1 | CIS-DIIODO- (TRANS-L-1,2-CYCLOHEXANEDIAMINE) PLATINUM (II) COMPLEX AND PROCESSES FOR PREPARING HIGH PURITY OXALIPLATIN | Sicor Inc. (US) | 2006-05-24 | — | — | EP | disclosed |
| WO-2006023154-A1 | CIS-DIIODO- (TRANS-L-1,2-CYCLOHEXANEDIAMINE) PLATINUM (II) COMPLEX AND PROCESSES FOR PREPARING HIGH PURITY OXALIPLATIN | SICOR, INC. (US) | 2006-03-02 | — | — | WO | disclosed |
| US-20060041012-A1 | Cis-diiodo-(trans-l-1,2-cyclohexanediamine) platinum (II) complex and processes for preparing high purity oxaliplatin | SICOR, INC. | 2006-02-23 | — | — | US | disclosed |
| US-20060041012-A1 | Cis-diiodo-(trans-l-1,2-cyclohexanediamine) platinum (II) complex and processes for preparing high purity oxaliplatin | SICOR, INC. | 2006-02-23 | — | — | US | disclosed |
| US-5008419-A | Novel platinum complex | SS PHARMACEUTICAL CO., LTD. (JP) | 1991-04-16 | — | — | US | disclosed |