⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177559 | 0.75 | ALDH1A1 (0.40) | — | |
| SCHEMBL5374899 | 0.70 | ALDH1A1 (0.43) | — | |
| SCHEMBL471023 | 0.69 | — | — | |
| SCHEMBL10033375 | 0.69 | — | — | |
| SCHEMBL10292496 | 0.69 | ALDH1A1 (0.35) | — | |
| SCHEMBL26684 | 0.69 | — | — | |
| SCHEMBL6810633 | 0.69 | — | — | |
| SCHEMBL3483517 | 0.68 | ELANE (0.38) | — | |
| Ammonia Solution, Strong SCHEMBL6253681 | 0.67 | — | — | |
| Phosphine SCHEMBL11162239 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110059941-A1 | 2-PHENYL SUBSTITUTED IMIDAZOL [4,5B] PYRIDINE/PYRAZINE AND PURINE DERIVATIVES AS GLUCOKINASE MODULATORS | ASTRAZENECA AB (SE) | 2011-03-10 | — | — | US | claimed |
| EP-1891069-A1 | 2-PHENYL SUBSTITUTED IMIDAZOL [4,5B]PYRIDINE/ PYRAZINE AND PURINE DERIVATIVES AS GLUCOKINASE MODULATORS | AstraZeneca AB (SE) | 2008-02-27 | — | — | EP | claimed |
| WO-2006125958-A1 | 2-PHENYL SUBSTITUTED IMIDAZOL [4 , 5B] PYRIDINE/ PYRAZINE AND PURINE DERIVATIVES AS GLUCOKINASE MODULATORS | ASTRAZENECA AB (SE) | 2006-11-30 | — | — | WO | claimed |
| CN-112384509-B | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-115666567-A | Furin inhibitors for the treatment of coronavirus infection | BP资产V股份有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-112384509-A | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-02-19 | — | — | CN | disclosed |
| EP-3215505-B1 | PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE | Bayer Pharma AG (DE) | 2019-07-24 | — | — | EP | disclosed |
| CN-109328188-A | 2 inhibitor of ZESTE enhancer homologue | 葛兰素史密斯克莱知识产权（第2 号）有限公司 | 2019-02-12 | — | — | CN | disclosed |
| CN-105655644-B | Lithium ion battery and preparation method thereof | 东莞新能源科技有限公司 | 2019-01-22 | — | — | CN | disclosed |
| US-10118930-B2 | Piperidinylpyrazolopyrimidinones and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-11-06 | — | — | US | disclosed |
| CN-107849032-A | The inhibitor of ZESTE enhancers homologue 2 | 葛兰素史密斯克莱知识产权（第2 号）有限公司 | 2018-03-27 | — | — | CN | disclosed |
| WO-1993016985-A1 | CYANO-OXIME ETHERS, PROCESS FOR PRODUCING THEM, AGENTS CONTAINING THEM AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1993-09-02 | — | — | WO | disclosed |
| US-5194662-A | Insecticides, fungicides for plants | BASF AKTIENGESELLSCHAFT (DE) | 1993-03-16 | — | — | US | disclosed |
| US-5064818-A | PESTICIDAL PYRIMIDINYL (THIONO) (THIO)-PHOSPHORIC (PHOSPHONIC)ACID (AMIDE) ESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-11-12 | — | — | US | disclosed |
| EP-0395968-A1 | (Thiono) (thio)pyrimidyl-phosphonyl (phosphonic) ester (amid) | BAYER AG (DE) | 1990-11-07 | — | — | EP | disclosed |
| EP-0213377-B1 | PHOSPHORIC (PHOSPHONIC) ACID ESTERS | BAYER AG (DE) | 1989-02-15 | — | — | EP | disclosed |
| EP-0213377-A1 | Phosphoric (phosphonic) acid esters | BAYER AG (DE) | 1987-03-11 | — | — | EP | disclosed |
| EP-0173857-A1 | Fungicidal agent based on phosphoryloximinoacetamide | BAYER AG (DE) | 1986-03-12 | — | — | EP | disclosed |
| EP-0132676-A2 | Phosphoric or phosphonic acid esters | BAYER AG (DE) | 1985-02-13 | — | — | EP | disclosed |
| EP-0100476-A2 | Phosphoric-acid esters, process for their preparation and their use as pesticides | BAYER AG (DE) | 1984-02-15 | — | — | EP | disclosed |