SCHEMBL4413629

SCHEMBL4413629

CC1CC(C)(C)CC(C)(C)C1

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALOX12 P18054 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL910279 0.85
Ammonia Solution, Strong SCHEMBL4429133 0.82 ESR1 (0.36) ESR1ESR2ALDH1A1KDM4EALOX12
SCHEMBL6053151 0.80 ESR1 (0.42) ESR1ESR2ALDH1A1
SCHEMBL21085897 0.80 ESR1 (0.38) ESR1ESR2
SCHEMBL635664 0.80 ESR1 (0.38) ESR1ESR2CYP2D6
SCHEMBL540773 0.80 ESR1 (0.38) ESR1ESR2CYP2D6
SCHEMBL4096134 0.80 ESR1 (0.38) ESR1ESR2CYP2D6
SCHEMBL19222745 0.80 ESR1 (0.38) ESR1ESR2
SCHEMBL1935108 0.80 ESR1 (0.42) ESR1ESR2ALDH1A1
SCHEMBL20385069 0.80 ESR1 (0.38) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023215803-A2 CYTOCHROME BD OXIDASE INHIBITORS AND USES THEREOF UNIVERSITY OF NOTRE DAME DU LAC (US) 2023-11-09 WO disclosed
US-20230193027-A1 RESIN, COMPOSITION THEREOF AND COPPER CLAD LAMINATE MADE THEREOF A.C.R. TECH CO., LTD. (TW) 2023-06-22 US disclosed
WO-2023001717-A1 AN ADDITIVE MIXTURE FOR STABILIZATION OF ORGANIC MATERIAL BASF SE (DE) 2023-01-26 WO disclosed
US-20210191012-A1 OPTICAL FILTER AND IMAGING DEVICE AGC Inc. (JP) 2021-06-24 US disclosed
EP-2131828-A2 AMPA AND NMDA RECEPTOR ANTAGONISTS FOR NEURODEGENERATIVE DISEASES Eisai R&D Management Co., Ltd. (JP) 2009-12-16 EP disclosed
WO-2008111590-A2 AMPA AND NMDA RECEPTOR ANTAGONISTS FOR NEURODEGENERATIVE DISEASES EISAI R & D MANAGEMENT CO., LTD. (JP) 2008-09-18 WO disclosed