Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.56 |
| ▸ | GRM8 | O00222 | 1/20 | 0.56 |
| ▸ | GRM6 | O15303 | 1/20 | 0.56 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.56 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.56 |
| ▸ | GRM5 | P41594 | 1/20 | 0.56 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.56 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.56 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.56 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.56 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.56 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.56 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.56 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.56 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.56 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4414000 | 1.00 | GSR (0.56) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL472936 | 1.00 | GSR (0.56) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL25661134 | 1.00 | GSR (0.56) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL8068164 | 0.88 | GSR (0.68) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL602426 | 0.88 | GSR (0.68) | GSRGRM8GRM6GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL11780148 | 0.85 | GSR (0.65) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL208933 | 0.84 | GSR (0.60) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL208932 | 0.84 | GSR (0.60) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL19758974 | 0.84 | GSR (0.60) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL17227466 | 0.83 | GSR (0.56) | GSRGRM8GRM6GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635765-B2 | Nucleotide sequences coding polypeptide for use in generation of preferential antibiotics; polynucleotide which encodes a domain of a ramoplanin nonribosomal peptide synthetase | THALLION PHARMACEUTICALS, INC. (CA) | 2009-12-22 | — | — | US | disclosed |
| US-7078185-B2 | Gene encoding a nonribosomal peptide synthetase for the production of ramoplanin | ECOPIA BIOSCIENCES INC. (CA) | 2006-07-18 | — | — | US | disclosed |
| US-20050287641-A1 | Nucleotide sequences coding polypeptide for use in generation of preferential antibiotics; polynucleotide which encodes a domain of a ramoplanin nonribosomal peptide synthetase | ECOPIA BIOSCIENCES, INC. | 2005-12-29 | — | — | US | disclosed |
| EP-1326983-B1 | GENE CLUSTER FOR RAMOPLANIN BIOSYNTHESIS | ECOPIA BIOSCIENCES INC (CA) | 2005-04-06 | — | — | EP | disclosed |
| EP-1326983-A2 | GENE CLUSTER FOR RAMOPLANIN BIOSYNTHESIS | Ecopia Biosciences Inc. (CA) | 2003-07-16 | — | — | EP | disclosed |
| US-20020164747-A1 | Gene cluster for ramoplanin biosynthesis | ECOPIA BIOSCIENCES INC. | 2002-11-07 | — | — | US | disclosed |
| WO-2002031155-A2 | GENE CLUSTER FOR RAMOPLANIN BIOSYNTHESIS | ECOPIA BIOSCIENCES INC. (CA) | 2002-04-18 | — | — | WO | disclosed |
| US-5914313-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1999-06-22 | — | — | US | disclosed |