Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.56 |
| ▸ | GRM8 | O00222 | 1/20 | 0.56 |
| ▸ | GRM6 | O15303 | 1/20 | 0.56 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.56 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.56 |
| ▸ | GRM5 | P41594 | 1/20 | 0.56 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.56 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.56 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.56 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.56 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.56 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.56 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.56 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.56 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.56 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4414003 | 1.00 | GSR (0.56) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL4414000 | 1.00 | GSR (0.56) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL25661134 | 1.00 | GSR (0.56) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL8068164 | 0.88 | GSR (0.68) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL602426 | 0.88 | GSR (0.68) | GSRGRM8GRM6GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL11780148 | 0.85 | GSR (0.65) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL208933 | 0.84 | GSR (0.60) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL208932 | 0.84 | GSR (0.60) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL19758974 | 0.84 | GSR (0.60) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL17227466 | 0.83 | GSR (0.56) | GSRGRM8GRM6GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11779634-B2 | Fungal iron acquisition inhibitors and uses thereof | CASE WESTERN RESERVE UNIVERSITY (US) | 2023-10-10 | — | — | US | disclosed |
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | RAYZEBIO, INC. | 2023-05-25 | — | — | US | disclosed |
| US-20220211820-A1 | FUNGAL IRON ACQUISITION INHIBITORS AND USES THEREOF | UNIV CASE WESTERN RESERVE (US) | 2022-07-07 | — | — | US | disclosed |
| US-11229685-B2 | Fungal iron acquisition inhibitors and uses thereof | CASE WESTERN RESERVE UNIVERSITY (US) | 2022-01-25 | — | — | US | disclosed |
| US-10548860-B2 | HIF-1 modulator paint formulation and uses thereof | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-02-04 | — | — | US | disclosed |
| US-20190192452-A1 | HIF-1 MODULATOR PAINT FORMULATION AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2019-06-27 | — | — | US | disclosed |
| US-10220009-B2 | HIF-1 modulator paint formulation and uses thereof | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2019-03-05 | — | — | US | disclosed |
| US-9763899-B2 | Iron chelators and use thereof for reducing transplant failure during rejection episodes | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2017-09-19 | — | — | US | disclosed |
| US-20170252310-A9 | Iron Chelators and Use Thereof for Reducing Transplant Failure During Rejection Episodes | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-09-07 | — | — | US | disclosed |
| US-20160184244-A1 | Iron Chelators and Use Thereof for Reducing Transplant Failure During Rejection Episodes | UNIV LELAND STANFORD JUNIOR (US) | 2016-06-30 | — | — | US | disclosed |
| WO-2009086592-A1 | METHOD OF INCREASING METABOLISM | GARVAN INSTITUTE OF MEDICAL RESEARCH (AU) | 2009-07-16 | — | — | WO | disclosed |
| EP-2043636-A2 | (COMBI) COMPOSITIONS FOR THE TREATMENT OF MUCORMYCOSIS COMPRISING IRON CHELATOR AND ANTIFUNGAL AGENT | Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (US) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008008537-A2 | COMBI) COMPOSITIONS FOR THE TREATMENT OF MUCORMYCOSIS. COMPRISING IRON CHELATOR AND ANTIFUNGAL AGENT | LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER (US) | 2008-01-17 | — | — | WO | disclosed |
| US-7078185-B2 | Gene encoding a nonribosomal peptide synthetase for the production of ramoplanin | ECOPIA BIOSCIENCES INC. (CA) | 2006-07-18 | — | — | US | disclosed |
| US-20050287641-A1 | Nucleotide sequences coding polypeptide for use in generation of preferential antibiotics; polynucleotide which encodes a domain of a ramoplanin nonribosomal peptide synthetase | ECOPIA BIOSCIENCES, INC. | 2005-12-29 | — | — | US | disclosed |
| EP-1326983-B1 | GENE CLUSTER FOR RAMOPLANIN BIOSYNTHESIS | ECOPIA BIOSCIENCES INC (CA) | 2005-04-06 | — | — | EP | disclosed |
| EP-1326983-A2 | GENE CLUSTER FOR RAMOPLANIN BIOSYNTHESIS | Ecopia Biosciences Inc. (CA) | 2003-07-16 | — | — | EP | disclosed |
| US-20020164747-A1 | Gene cluster for ramoplanin biosynthesis | ECOPIA BIOSCIENCES INC. | 2002-11-07 | — | — | US | disclosed |
| WO-2002031155-A2 | GENE CLUSTER FOR RAMOPLANIN BIOSYNTHESIS | ECOPIA BIOSCIENCES INC. (CA) | 2002-04-18 | — | — | WO | disclosed |
| US-5914313-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1999-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11229685-B2 | Fungal iron acquisition inhibitors and uses thereof | SLC40A1, SLC30A6, SLC30A7 | GSR 578/4885GRM8 4253/4885GRM6 3858/4885 |
| US-20220211820-A1 | FUNGAL IRON ACQUISITION INHIBITORS AND USES THEREOF | SLC40A1, SLC30A6, SLC30A7 | GSR 578/4885GRM8 4253/4885GRM6 3858/4885 |
| US-11779634-B2 | Fungal iron acquisition inhibitors and uses thereof | SLC40A1, SLC30A6, SLC30A7 | GSR 578/4885GRM8 4253/4885GRM6 3858/4885 |
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | PAICS, LNPEP, DNPEP | GSR 1986/4885GRM8 2231/4885GRM6 2966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.