Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 3/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382252 | 0.73 | ACP3 (0.42) | ACP3SRCCES1CES2PTPN1 | |
| SCHEMBL28258273 | 0.70 | ACP3 (0.40) | ACP3SRCCES1CES2PTPN1 | |
| SCHEMBL28088550 | 0.67 | POLB (0.39) | ACP3SRCCES1CES2PTPN1 | |
| SCHEMBL17956469 | 0.64 | TSHR (0.43) | SRCCES1CES2CYP2D6LMNA | |
| SCHEMBL5042134 | 0.64 | ATM (0.42) | SRCCES1CES2CYP2D6 | |
| SCHEMBL17363627 | 0.64 | HPGD (0.35) | ACP3SRCHPGDCYP2D6LMNA | |
| SCHEMBL28837273 | 0.63 | SRC (0.39) | ACP3SRCCES1CES2PTPN1 | |
| SCHEMBL4274555 | 0.63 | SRC (0.39) | ACP3SRCCES1CES2PTPN1 | |
| SCHEMBL29009915 | 0.63 | CYP2D6 (0.43) | ACP3SRCCES1CES2CYP2D6 | |
| SCHEMBL15114536 | 0.63 | LMNA (0.47) | ACP3SRCCES1CES2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009144548-A1 | IMIDAZO [2,1-B] PURINE DERIVATIVES AS TRPA1 MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2009-12-03 | — | — | WO | disclosed |