SCHEMBL4414162

SCHEMBL4414162

Nc1cc(N)c(N)cc1N.Nc1ccc(C2(c3ccc(N)cc3)c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.85
KMT2A Q03164 4/20 0.85
SMN1; SMN2 Q16637 4/20 0.85
LMNA P02545 3/20 0.85
MAPT P10636 3/20 0.85
KDM4E B2RXH2 2/20 0.85
OPRK1 P41145 1/20 0.85
POLB P06746 4/20 0.46
ESR1 P03372 1/20 0.46
ESR2 Q92731 1/20 0.46
PDK2 Q15119 5/20 0.42
ALDH1A1 P00352 4/20 0.36
NPC1 O15118 4/20 0.36
RAB9A P51151 3/20 0.36
HPGD P15428 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.34
CYP3A4 P08684 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
TSHR P16473 2/20 0.34
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL105428 0.92 MAPT (1.00) MEN1KMT2ASMN1; SMN2LMNAMAPT
SCHEMBL29426418 0.92 MAPT (1.00) MEN1KMT2ASMN1; SMN2LMNAMAPT
SCHEMBL29392989 0.92 MAPT (1.00) MEN1KMT2ASMN1; SMN2LMNAMAPT
Ammonia Solution, Strong SCHEMBL2046821 0.90 MEN1 (0.96) MEN1KMT2ASMN1; SMN2LMNAMAPT
Ammonia Solution, Strong SCHEMBL7052845 0.90 MEN1 (0.96) MEN1KMT2ASMN1; SMN2LMNAMAPT
SCHEMBL17819277 0.88 MAPT (0.92) MEN1KMT2ASMN1; SMN2LMNAMAPT
SCHEMBL31537252 0.88 MAPT (0.92) MEN1KMT2ASMN1; SMN2LMNAMAPT
SCHEMBL2450310 0.87 SMN1; SMN2 (0.81) MEN1KMT2ASMN1; SMN2LMNAMAPT
Benzidine SCHEMBL1656523 0.86 KDM4E (0.88) MEN1KMT2ASMN1; SMN2LMNAMAPT
SCHEMBL29128951 0.86 KDM4E (0.88) MEN1KMT2ASMN1; SMN2LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024037851-A1 USE OF ADDITIVES FOR IMPROVING THE PROCESSING OF POLYETHYLENES BASF SE (DE) 2024-02-22 WO disclosed
EP-2026965-A1 MONO- AND MULTI-LAYER BLOWN FILMS Ciba Holding Inc. (CH) 2009-02-25 EP disclosed
EP-1928936-A1 PROCESS FOR IMPROVING THE FLOW PROPERTIES OF POLYMER MELTS Ciba Holding Inc. (CH) 2008-06-11 EP disclosed
WO-2007068766-A1 MONO- AND MULTI-LAYER BLOWN FILMS CIBA HOLDING INC. (CH) 2007-06-21 WO disclosed
WO-2007039471-A1 PROCESS FOR IMPROVING THE FLOW PROPERTIES OF POLYMER MELTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2007-04-12 WO disclosed