Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL7052845

N.Nc1ccc(C2(c3ccc(N)cc3)c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.96
KMT2A Q03164 3/20 0.96
MAPT P10636 3/20 0.96
SMN1; SMN2 Q16637 3/20 0.96
KDM4E B2RXH2 2/20 0.96
LMNA P02545 2/20 0.96
OPRK1 P41145 1/20 0.96
POLB P06746 2/20 0.50
ESR1 P03372 1/20 0.46
ESR2 Q92731 1/20 0.46
PDK2 Q15119 4/20 0.42
TSHR P16473 2/20 0.36
TDP1 Q9NUW8 3/20 0.36
CYP3A4 P08684 2/20 0.36
TAAR1 Q96RJ0 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ALDH1A1 P00352 4/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL2046821 1.00 MEN1 (0.96) MEN1KMT2AMAPTSMN1; SMN2KDM4E
SCHEMBL105428 0.98 MAPT (1.00) MEN1KMT2AMAPTSMN1; SMN2KDM4E
SCHEMBL29392989 0.98 MAPT (1.00) MEN1KMT2AMAPTSMN1; SMN2KDM4E
SCHEMBL29426418 0.98 MAPT (1.00) MEN1KMT2AMAPTSMN1; SMN2KDM4E
SCHEMBL17819277 0.94 MAPT (0.92) MEN1KMT2AMAPTSMN1; SMN2KDM4E
SCHEMBL31537252 0.94 MAPT (0.92) MEN1KMT2AMAPTSMN1; SMN2KDM4E
Benzidine SCHEMBL1656523 0.92 KDM4E (0.88) MEN1KMT2AMAPTSMN1; SMN2KDM4E
SCHEMBL29128951 0.92 KDM4E (0.88) MEN1KMT2AMAPTSMN1; SMN2KDM4E
SCHEMBL4414162 0.90 MEN1 (0.85) MEN1KMT2AMAPTSMN1; SMN2KDM4E
SCHEMBL8984568 0.88 MEN1 (0.81) MEN1KMT2AMAPTSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0851887-B1 EPOXY RESIN COMPOSITIONS, PREPREGS, CURED COMPOSITES, AND METHODS OF MAKING THE SAME MINNESOTA MINING & MFG (US) 2003-04-23 EP claimed
US-6054221-A A FLUORENE AMINE CURATIVE PARTIALLY MELT DISSOLVED AND PARTIALLY DISPERSED AS A SOLID IN AN AROMATIC POLYEPOXIDE; PREPREGS HAVING TACK WITH GOOD SHELF LIFE PROPERTIES; NON-DIFFUSING; COMPARABLE GLASS TRANSITION TEMPERATURES 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-04-25 US claimed
US-6007917-A FOR MAKING LIGHTWEIGHT, HIGH STRENGH AIRCRAFT COMPONENTS 3M INNOVATIVE PROPERTIES COMPANY (US) 1999-12-28 US claimed
US-5728755-A EXHIBIT TACK AND GOOD SHELF LIFE, LITTLE RESIN MIGRATION AND GLASS TRANSITION TEMPERATURE SIMILAR TO THOSE CURED NEAT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-17 US claimed