Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 11/20 | 0.67 |
| ▸ | PTPN2 | P17706 | 7/20 | 0.60 |
| ▸ | PTPRC | P08575 | 1/20 | 0.56 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.48 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2693268 | 0.83 | PTPN1 (0.47) | PTPN1PTPN2PTPRCPTPN5UGT2B7 | |
| SCHEMBL2691376 | 0.81 | PTPN1 (1.00) | PTPN1PTPN2PTPRC | |
| SCHEMBL3746043 | 0.80 | PTPN1 (0.72) | PTPN1PTPN2PTPRC | |
| SCHEMBL4566574 | 0.79 | UGT2B7 (0.43) | PTPN1PTPN2PTPRCPTPN5UGT2B7 | |
| SCHEMBL5021024 | 0.78 | PTPN1 (0.71) | PTPN1PTPN2PTPRC | |
| SCHEMBL2691065 | 0.77 | PTPN1 (0.69) | PTPN1PTPN2PTPRC | |
| SCHEMBL4410745 | 0.77 | PTPN1 (0.69) | PTPN1PTPN2PTPRC | |
| SCHEMBL2690547 | 0.76 | PTPN1 (0.67) | PTPN1PTPN2PTPRC | |
| SCHEMBL3177750 | 0.76 | PTPN1 (0.73) | PTPN1PTPN2PTPRC | |
| SCHEMBL15095636 | 0.76 | PTPN1 (0.73) | PTPN1PTPN2PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114971-B1 | FUSED AROMATIC PTP-1B INHIBITORS | KANEQ PHARMA INC (CA) | 2015-06-17 | — | — | EP | disclosed |
| US-8481742-B2 | Fused aromatic PTP-1B inhibitors | KANEQ PHARMA INC. (CA) | 2013-07-09 | — | — | US | disclosed |
| EP-2114971-A1 | FUSED AROMATIC PTP-1B INHIBITORS | Merck Frosst Canada Ltd. (CA) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008089581-A1 | FUSED AROMATIC PTP-1B INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2008-07-31 | — | — | WO | disclosed |