SCHEMBL4414942

SCHEMBL4414942

CC(=O)Nc1cc(NC(C)=O)c2ccccc2n1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.55
HSP90AA1 P07900 1/20 0.55
HSP90AB1 P08238 1/20 0.55
KMT2A Q03164 6/20 0.53
MEN1 O00255 4/20 0.53
HTT P42858 2/20 0.52
ADORA3 P0DMS8 4/20 0.51
ADORA1 P30542 2/20 0.51
ADORA2B P29275 1/20 0.51
ADORA2A P29274 1/20 0.51
ABCB1 P08183 1/20 0.51
ABCC1 P33527 1/20 0.51
ABCG2 Q9UNQ0 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.50
MAPT P10636 2/20 0.50
LMNA P02545 2/20 0.50
KDM1A O60341 1/20 0.50
MITF O75030 1/20 0.50
POLB P06746 1/20 0.50
RAD52 P43351 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16984472 0.84 KDM4E (0.55) KDM4EHSP90AA1HSP90AB1KMT2AMEN1
SCHEMBL5053541 0.84 HTT (0.73) KDM4EKMT2AMEN1HTTSMN1; SMN2
Acetic Acid SCHEMBL9849558 0.83 KDM4E (0.54) KDM4EHSP90AA1HSP90AB1KMT2AMEN1
SCHEMBL16974190 0.83 KDM4E (0.54) KDM4EHSP90AA1HSP90AB1KMT2AMEN1
Potassium SCHEMBL30101822 0.83 KDM4E (0.54) KDM4EHSP90AA1HSP90AB1KMT2AMEN1
SCHEMBL28233531 0.83 KDM4E (0.54) KDM4EHSP90AA1HSP90AB1KMT2AMEN1
SCHEMBL13036676 0.80 ALOX15 (0.60) KDM4EHSP90AA1HSP90AB1KMT2AMEN1
SCHEMBL27299051 0.80 KMT2A (0.49) KDM4EKMT2AMEN1HTTABCB1
SCHEMBL18232565 0.80 PDE10A (0.54) KDM4EHSP90AA1HSP90AB1KMT2AMEN1
SCHEMBL28404749 0.79 KDM4E (0.65) KDM4EHSP90AA1HSP90AB1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed