Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 9/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 8/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 5/20 | 1.00 |
| ▸ | APP | P05067 | 5/20 | 1.00 |
| ▸ | NR4A2 | P43354 | 2/20 | 1.00 |
| ▸ | ABCB11 | O95342 | 1/20 | 1.00 |
| ▸ | CHRM2 | P08172 | 1/20 | 1.00 |
| ▸ | HTR1A | P08908 | 1/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 1/20 | 1.00 |
| ▸ | DRD2 | P14416 | 1/20 | 1.00 |
| ▸ | ADRA2C | P18825 | 1/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 1/20 | 1.00 |
| ▸ | PTGS2 | P35354 | 1/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 1/20 | 1.00 |
| ▸ | HTR2B | P41595 | 1/20 | 1.00 |
| ▸ | CYP2J2 | P51589 | 1/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 1.00 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 1.00 |
| ▸ | CYP2C8 | P10632 | 6/20 | 0.98 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.98 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amodiaquine SCHEMBL29441086 | 1.00 | CYP2D6 (1.00) | CYP2D6CYP1A2KCNH2APPNR4A2 | |
| Amodiaquine SCHEMBL29425350 | 1.00 | CYP2D6 (1.00) | CYP2D6CYP1A2KCNH2APPNR4A2 | |
| Amodiaquine SCHEMBL317888 | 0.99 | CYP2D6 (1.00) | CYP2D6CYP1A2KCNH2APPNR4A2 | |
| Amodiaquine SCHEMBL12094969 | 0.99 | CYP2D6 (1.00) | CYP2D6CYP1A2KCNH2APPNR4A2 | |
| Amodiaquine SCHEMBL29430175 | 0.99 | CYP2D6 (1.00) | CYP2D6CYP1A2KCNH2APPNR4A2 | |
| Amodiaquine SCHEMBL29788983 | 0.99 | CYP2D6 (1.00) | CYP2D6CYP1A2KCNH2APPNR4A2 | |
| Amodiaquine SCHEMBL1491204 | 0.98 | CYP2D6 (1.00) | CYP2D6CYP1A2KCNH2APPNR4A2 | |
| Amodiaquine SCHEMBL284774 | 0.98 | CYP2D6 (0.96) | CYP2D6CYP1A2KCNH2APPNR4A2 | |
| Amodiaquine SCHEMBL30903900 | 0.98 | CYP2D6 (1.00) | CYP2D6CYP1A2KCNH2APPNR4A2 | |
| SCHEMBL20536537 | 0.94 | CYP2D6 (0.88) | CYP2D6CYP1A2KCNH2APPNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 8281 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4255391-B1 | LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION | METRIOPHARM AG (CH) | 2026-05-06 | — | — | EP | claimed |
| EP-4680248-A1 | PRODUCTS OF MANUFACTURE AND THERAPEUTIC COMPOSITIONS FOR TREATING, AMELIORATING OR PREVENTING VIRAL INFECTIONS AND METHODS FOR MAKING AND USING THEM | Topelia Aust Limited (ACN 652 771 670) (AU) | 2026-01-21 | — | — | EP | claimed |
| EP-4680608-A1 | 2,6-DIHYDRO-7H-PYRAZOLO[3,4-C]PYRIDIN-7-ONE DERIVATIVES AS ANTI-MALARIAL AGENTS | MMV Medicines for Malaria Venture (CH) | 2026-01-21 | — | — | EP | claimed |
| EP-4677612-A1 | METHODS FOR DETERMINING DRUG CANDIDATES | mosaiques diagnostics & therapeutics AG (DE) | 2026-01-14 | — | — | EP | claimed |
| US-12509439-B2 | Anti-malarial agents | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2025-12-30 | — | — | US | claimed |
| US-20250388603-A1 | ANTIMALARIAL COMPOUNDS | SCRIPPS RESEARCH INST (US) | 2025-12-25 | — | — | US | claimed |
| EP-4659817-A2 | LIPOSOME COMPOSITION FOR USE IN PERITONEAL DIALYSIS | Versantis AG (CH) | 2025-12-10 | — | — | EP | claimed |
| WO-2025244856-A1 | METHODS AND COMPOSITIONS RELATING TO ELQ COMPOUNDS | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2025-11-27 | — | — | WO | claimed |
| EP-3625238-B1 | NOVEL SPIRO-LACTAM COMPOUNDS, PROCESS AND USES THEREOF | UNIV DE COIMBRA (PT) | 2025-11-26 | — | — | EP | claimed |
| US-12458694-B2 | Methods for treatment of accelerated atherosclerosis and rheumatoid arthritis with an anti-Apo B100 antibody | ABCENTRA, LLC (US) | 2025-11-04 | — | — | US | claimed |
| EP-0338532-A2 | N-alkylamino derivates of aromatic, tricyclic compounds in the treatment of drug-resistant protozoal infections | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-10-25 | — | — | EP | claimed |
| WO-1989008119-A1 | HIGH MOLECULAR WEIGHT PRODRUG DERIVATIVES OF ANTI-INFLAMMATORY DRUGS | SELCH LARSEN CLAUS (DK) | 1989-09-08 | — | — | WO | claimed |
| EP-0331471-A1 | High molecular weight prodrug derivatives of antiinflammatory drugs | Larsen, Claus Selch (DK) | 1989-09-06 | — | — | EP | claimed |
| US-4806537-A | Use of amodiaquin and related compounds in treatment of nervous system degeneration | CITY OF HOPE (US) | 1989-02-21 | — | — | US | claimed |
| EP-0290959-A2 | Drug mixture for prophylaxis and therapy of malaria | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-17 | — | — | EP | claimed |
| EP-0037175-B1 | PHARMACEUTICAL COMPOSITIONS | EFAMOL LIMITED (GB) | 1988-02-10 | — | — | EP | claimed |
| EP-0152379-A2 | Process for preparing pharmaceutical compositions containing unilamellar liposomes | CIBA-GEIGY AG (CH) | 1985-08-21 | — | — | EP | claimed |
| EP-0035856-B1 | PHARMACEUTICAL AND DIETARY COMPOSITIONS | EFAMOL LIMITED (GB) | 1984-07-04 | — | — | EP | claimed |
| EP-0037175-A1 | Pharmaceutical compositions | EFAMOL LIMITED (GB) | 1981-10-07 | — | — | EP | claimed |
| EP-0035856-A2 | Pharmaceutical and dietary compositions | EFAMOL LIMITED (GB) | 1981-09-16 | — | — | EP | claimed |