Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6 | P05231 | 8/20 | 0.45 |
| ▸ | PGR | P06401 | 9/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4426059 | 0.94 | IL6 (0.46) | IL6PGRNR3C1ESR1AR | |
| SCHEMBL4418092 | 0.93 | IL6 (0.47) | IL6PGRNR3C1ESR1AR | |
| SCHEMBL4415311 | 0.90 | IL6 (0.47) | IL6PGRNR3C1ESR1AR | |
| SCHEMBL4420373 | 0.88 | MAPT (0.47) | IL6PGRNR3C1ESR1AR | |
| SCHEMBL4419607 | 0.88 | IL6 (0.45) | IL6PGRNR3C1ESR1AR | |
| SCHEMBL4420398 | 0.87 | MAPT (0.49) | IL6PGRNR3C1ESR1AR | |
| SCHEMBL1316189 | 0.87 | IL6 (0.50) | IL6PGRNR3C1ESR1AR | |
| SCHEMBL1314982 | 0.86 | IL6 (0.51) | IL6PGRNR3C1ESR1AR | |
| SCHEMBL4423701 | 0.86 | IL6 (0.46) | IL6PGRNR3C1ESR1AR | |
| SCHEMBL2393223 | 0.86 | IL6 (0.48) | IL6PGRNR3C1ESR1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8440660-B2 | Method for treating a disease related to the glucocorticoid receptor | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2013-05-14 | — | — | US | disclosed |
| EP-2085387-B1 | NOVEL 1,2-DIHYDROQUINOLINE DERIVATIVE HAVING SUBSTITUTED PHENYLCHALCOGENO LOWER ALKYL GROUP AND ESTER-INTRODUCED PHENYL GROUP AS SUBSTITUENTS | SANTEN PHARMACEUTICAL CO LTD (JP) | 2013-04-10 | — | — | EP | disclosed |
| EP-2085387-A1 | NOVEL 1,2-DIHYDROQUINOLINE DERIVATIVE HAVING SUBSTITUTED PHENYLCHALCOGENO LOWER ALKYL GROUP AND ESTER-INTRODUCED PHENYL GROUP AS SUBSTITUENTS | Santen Pharmaceutical Co., Ltd (JP) | 2009-08-05 | — | — | EP | disclosed |